Correlating ISEND and Tumor Mutation Burden (TMB) with Clinical Outcomes of Advanced Non-Small Cell Lung Cancer (ANSCLC) Patients on Nivolumab

被引:0
|
作者
Park, W. [1 ]
Lopes, G. [1 ]
Kwon, D. [2 ]
Florou, V. [1 ]
Chae, Y. K. [3 ]
Warsch, J. [4 ]
Ishkanian, A. [5 ]
Jahanzeb, M. [6 ]
Mudad, R. [1 ]
机构
[1] Univ Miami, Sylvester Comprehens Canc Ctr, Hematol & Oncol, Miami, FL USA
[2] Univ Miami, Sylvester Comprehens Canc Ctr, Dept Med Biostat & Bioinformat, Miami, FL USA
[3] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Div Hematol Oncol, Dev Therapeut Program, Chicago, IL 60611 USA
[4] Univ Miami, Sylvester Comprehens Canc Ctr, Radiol, Miami, FL USA
[5] Univ Miami, Sylvester Comprehens Canc Ctr, Radiat Oncol, Miami, FL USA
[6] Univ Miami, Sylvester Comprehens Canc Ctr, Med Oncol, Miami, FL USA
关键词
Tumor mutation burden; biomarker; Nivolumab;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P1.07-025
引用
收藏
页码:S2004 / S2005
页数:2
相关论文
共 50 条
  • [1] Real-World Clinical Outcomes in Patients with Advanced Non-Small Cell Lung Cancer (aNSCLC) in the US
    Nadler, E.
    Chang, J.
    Zhang, X.
    Aguilar, K.
    Zhou, J.
    Arondekar, B.
    Pawar, V.
    JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (01) : S38 - S39
  • [2] Uncommon EGFR mutations are associated with higher tumor mutation burden (TMB) in non-small cell lung cancer patients
    Shen, Xudong
    Zhang, Hushan
    Huang, Depei
    CANCER RESEARCH, 2020, 80 (16)
  • [3] EGFR Clonality and Tumor Mutation Burden (TMB) by Circulating Tumor DNA (ctDNA) Sequencing in Advanced Non-Small Cell Lung Cancer (NSCLC)
    Ai, X.
    Lin, Y.
    Zhang, J.
    Xie, C.
    Liu, A.
    Hu, X.
    Zhao, Q.
    Zang, Y.
    Rao, C.
    Hu, X.
    Chang, L.
    Li, Q.
    Guan, Y.
    Chen, R.
    Yi, X.
    Lu, S.
    JOURNAL OF THORACIC ONCOLOGY, 2018, 13 (10) : S412 - S413
  • [4] Clinical and Molecular Correlates of Tumor Mutation Burden in Non-Small Cell Lung Cancer
    Sharpnack, Michael F.
    Cho, Ju Hwan
    Johnson, Travis S.
    Otterson, Gregory A.
    Shields, Peter G.
    Huang, Kun
    Carbone, David P.
    He, Kai
    LUNG CANCER, 2020, 146 : 36 - 41
  • [5] Clinical significance of tumor mutation burden and DNA damage repair in advanced stage non-small cell lung cancer patients
    Zhang, H.
    Deng, Y-M
    Chen, Z-C
    Tang, Y-C
    Yang, S.
    Zhang, S-D
    Liang, J-M
    Wang, Y-G
    Wu, X.
    Zhang, R-W
    Feng, W-N
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2020, 24 (14) : 7664 - 7672
  • [6] Clinical Implications of Circulating Tumor DNA Tumor Mutational Burden (ctDNA TMB) in Non-Small Cell Lung Cancer
    Chae, Young Kwang
    Davis, Andrew A.
    Agte, Sarita
    Pan, Alan
    Simon, Nicholas I.
    Iams, Wade T.
    Cruz, Marcelo R.
    Tamragouri, Keerthi
    Rhee, Kyunghoon
    Mohindra, Nisha
    Villaflor, Victoria
    Park, Wungki
    Lopes, Gilberto
    Giles, Francis J.
    ONCOLOGIST, 2019, 24 (06): : 820 - 828
  • [7] Developing a Predictive Model for Clinical Outcomes of Advanced Non-Small Cell Lung Cancer Patients Treated With Nivolumab
    Park, Wungki
    Kwon, Deukwoo
    Saravia, Diana
    Desai, Amrita
    Vargas, Fernando
    El Dinali, Mohamed
    Warsch, Jessica
    Elias, Roy
    Chae, Young Kwang
    Kim, Dae Won
    Warsch, Sean
    Ishkanian, Adrian
    Ikpeazu, Chukwuemeka
    Mudad, Raja
    Lopes, Gilberto
    Jahanzeb, Mohammad
    CLINICAL LUNG CANCER, 2018, 19 (03) : 280 - +
  • [8] Clinical and genomic features of high tumor mutation burden in patients with non-small cell lung cancer.
    Qiu, Yuan
    Yang, Haihong
    Chen, Hanzhang
    Deng, Qiuhua
    Liu, Liping
    Xiao, Dakai
    Shao, Di
    Li, Weiwei
    Jiang, Wenxi
    Zhu, Changbin
    Lin, Yongping
    He, Jianxing
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)
  • [9] EGFR clonality and tumor mutation burden (TMB) analysis based on circulating tumor DNA (ctDNA) sequencing in advanced non-small cell lung cancer (NSCLC)
    Ai, X.
    Lin, Y.
    Liu, A.
    Xie, C.
    Hu, X.
    Zhao, Q.
    Zang, Y.
    Rao, C.
    Yi, X.
    Lu, S.
    JOURNAL OF THORACIC ONCOLOGY, 2018, 13 (04) : S27 - S28
  • [10] Continuum of care in advanced non-small lung cancer patients (ANSCLC).
    Mihaylova, Zhasmina
    Megdanova, Vera Georgieva
    Petrova, Veneta
    Petkova-Nelova, Dobromira
    Fakirova, Albena
    Dinev, Hristo
    JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)