The clinical aspects of limbal stem cell deficiency

被引：7
|
作者：
Grueterich, M. [1 ,2 ]
机构：
[1] Augenzentrum Munchen S, D-81479 Munich, Germany
[2] Augenklin LMU Munchen, Munich, Germany
来源：
OPHTHALMOLOGE | 2012年 / 109卷 / 09期
关键词：
Stem cells; Limbus; Limbal stem cell deficiency; Ocular surface defense mechanisms; Limbal epithelium; OCULAR SURFACE; EPITHELIUM; REMOVAL;
D O I：
10.1007/s00347-011-2508-5
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Stem cells are the ultimate source of the rapidly self-renewing corneal epithelium and are located in the basal layer of the limbal epithelium. Ocular surface defense mechanisms are important for the integrity of the ocular surface under normal and compromised conditions. A variety of diseases can compromise the stem cell pool causing an entity called limbal stem cell deficiency. Clinical symptoms can range from foreign body sensation and glare up to blindness. The exact diagnosis is crucial for adequate therapeutic measures.
引用
收藏
页码：850 / +
页数：6
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