Selective Mono- and Di-C(aryl)-H Sulfenylation of Benzamides by One-Pot Assembly of 8-Aminoquinoline, Benzoyl chlorides, and Thiophenols

被引：20

作者：

Liu, Yunyun ^{[1
]}

Huang, Meiying ^{[1
]}

Wei, Li ^{[1
]}

机构：

[1] Jiangxi Normal Univ, Coll Chem & Chem Engn, Nanchang 330022, Jiangxi, Peoples R China

来源：

ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 6卷 / 01期

基金：

中国国家自然科学基金;

关键词：

benzamides; copper; directing groups; selectivity; sulfenylation; H BOND FUNCTIONALIZATION; CATALYZED C-S; DIRECTING GROUP; INSTALLATION; ACTIVATION;

D O I：

10.1002/ajoc.201600491

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The domino reactions of 8-aminoquinoline, benzoyl chlorides, and thiophenols in one-pot provide sulfenylated benzamides efficiently without prior step of preparing N-qunolinyl benzamides. Besides the significantly improved step economy, the present one-pot method has also shown featured application in allowing the tunable mono-and disulfenylation of benzamides containing two identical C-H bonds by slightly modifying the reaction conditions.

引用

页码：41 / 43

页数：3