Management of Chronic Pain of Cervical Disc Herniation and Radiculitis with Fluoroscopic Cervical Interlaminar Epidural Injections

被引:37
|
作者
Manchikanti, Laxmaiah [1 ,2 ]
Cash, Kimberly A. [1 ]
Pampati, Vidyasagar [1 ]
Wargo, Bradley W. [1 ]
Malla, Yogesh [1 ]
机构
[1] Pain Management Ctr Paducah, Paducah, KY USA
[2] Univ Louisville, Louisville, KY 40292 USA
来源
关键词
Chronic neck pain; cervical disc herniation; upper extremity pain; cervical epidural injections; epidural steroids; local anesthetics; ACTIVE-CONTROLLED-TRIAL; MEDIAL BRANCH BLOCKS; LOW-BACK-PAIN; CLINICAL-PRACTICE GUIDELINES; RANDOMIZED CONTROLLED-TRIAL; CHRONIC NONCANCER PAIN; CHRONIC THORACIC PAIN; MANAGING CHRONIC PAIN; 2000-2010; TASK-FORCE; CHRONIC NECK PAIN;
D O I
10.7150/ijms.4444
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Study Design: A randomized, double-blind, active controlled trial. Objective: To evaluate the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids in the management of chronic neck pain and upper extremity pain in patients with disc herniation and radiculitis. Summary of Background Data: Epidural injections in managing chronic neck and upper extremity pain are commonly employed interventions. However, their long-term effectiveness, indications, and medical necessity, of their use and their role in various pathologies responsible for persistent neck and upper extremity pain continue to be debated, even though, neck and upper extremity pain secondary to disc herniation and radiculitis, is described as the common indication. There is also paucity of high quality literature. Methods: One-hundred twenty patients were randomly assigned to one of 2 groups: Group I patients received cervical interlaminar epidural injections of local anesthetic (lidocaine 0.5%, 5 mL); Group II patients received 0.5% lidocaine, 4 mL, mixed with 1 mL of nonparticulate betamethasone. Primary outcome measure was >= 50 improvement in pain and function. Outcome assessments included Numeric Rating Scale (NRS), Oswestry Disability Index (ODI), opioid intake, employment, and changes in weight. Results: Significant pain relief and functional status improvement (>= 50%) was demonstrated in 72% of patients who received local anesthetic only and 68% who received local anesthetic and steroids. In the successful group of participants, significant improvement was illustrated in 77% in local anesthetic group and 82% in local anesthetic with steroid group. Conclusions: Cervical interlaminar epidural injections with or without steroids may provide significant improvement in pain and function for patients with cervical disc herniation and radiculitis.
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页码:424 / 434
页数:11
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