Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use of Carbamazepine and Oxcarbazepine: 2017 Update

被引：191

作者：

Phillips, Elizabeth J. ^{[1
]}

Sukasem, Chonlaphat ^{[2
,3
]}

Whirl-Carrillo, Michelle ^{[4
]}

Mueller, Daniel J. ^{[5
,6
]}

Dunnenberger, Henry M. ^{[7
]}

Chantratita, Wasun ^{[8
,9
]}

Goldspiel, Barry ^{[10
]}

Chen, Yuan-Tsong ^{[11
,12
]}

Carleton, Bruce C. ^{[13
,14
]}

George, Alfred L. ^{[15
]}

Mushiroda, Taisei ^{[16
]}

Klein, Teri ^{[4
]}

Gammal, Roseann S. ^{[17
,18
]}

Pirmohamed, Munir ^{[19
]}

机构：

[1] Vanderbilt Univ, Med Ctr, Nashville, TN USA

[2] Mahidol Univ, Ramathibodi Hosp, Fac Med, Div Pharmacogen & Personalized Med,Dept Pathol, Bangkok, Thailand

[3] Ramathibodi Hosp, Fac Med, Somdech Phra Debaratana Med Ctr, Lab Pharmacogen, Bangkok, Thailand

[4] Stanford Univ, Dept Biomed Data Sci, Stanford, CA 94305 USA

[5] Ctr Addict & Mental Hlth, Campbell Family Mental Hlth Res Inst, Toronto, ON, Canada

[6] Univ Toronto, Dept Psychiat & Pharmacol & Toxicol, Toronto, ON, Canada

[7] NorthShore Univ HealthSyst, Ctr Mol Med, Evanston, IL USA

[8] Mahidol Univ, Ramathibodi Hosp, Fac Med, Virol Lab,Dept Pathol, Bangkok, Thailand

[9] Mahidol Univ, Ramathibodi Hosp, Ctr Med Genom, Bangkok, Thailand

[10] NIH, Pharm Dept, Ctr Clin, Bldg 10, Bethesda, MD 20892 USA

[11] Acad Sinica, Inst Biomed Sci, Taipei, Taiwan

[12] Duke Univ, Med Ctr, Dept Pediat, Durham, NC 27710 USA

[13] Univ British Columbia, Fac Med, Dept Pediat, Div Translat Therapeut, Vancouver, BC, Canada

[14] BC Childrens Hosp, Res Inst, Vancouver, BC, Canada

[15] Northwestern Univ, Dept Pharmacol, Feinberg Sch Med, Chicago, IL 60611 USA

[16] RIKEN, Ctr Integrat Med Sci, Lab Pharmacogen, Yokohama, Kanagawa, Japan

[17] MCPHS Univ, Dept Pharm Practice, Boston, MA USA

[18] St Jude Childrens Res Hosp, Dept Pharmaceut Sci, 332 N Lauderdale St, Memphis, TN 38105 USA

[19] Univ Liverpool, Dept Pharmacol, Liverpool, Merseyside, England

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2018年 / 103卷 / 04期

基金：

加拿大健康研究院; 英国医学研究理事会; 加拿大创新基金会; 美国国家卫生研究院;

关键词：

STEVENS-JOHNSON-SYNDROME; TOXIC EPIDERMAL NECROLYSIS; ADVERSE DRUG-REACTIONS; CYTOTOXIC T-CELLS; HLA-B-ASTERISK-1502; ALLELE; B GENOTYPE; HYPERSENSITIVITY REACTIONS; CUTANEOUS REACTIONS; JAPANESE PATIENTS; THAI POPULATION;

D O I：

10.1002/cpt.1004

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The variant allele HLA-B*15:02 is strongly associated with greater risk of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in patients treated with carbamazepine or oxcarbazepine. The variant allele HLA-A*31:01 is associated with greater risk of maculopapular exanthema, drug reaction with eosinophilia and systemic symptoms, and SJS/TEN in patients treated with carbamazepine. We summarize evidence from the published literature supporting these associations and provide recommendations for carbamazepine and oxcarbazepine use based on HLA genotypes.

引用

页码：574 / 581

页数：8

共 50 条

[1] Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update
Amstutz, Ursula
Henricks, Linda M.
Offer, Steven M.
Barbarino, Julia
Schellens, Jan H. M.
Swen, Jesse J.
Klein, Teri E.
McLeod, Howard L.
Caudle, Kelly E.
Diasio, Robert B.
Schwab, Matthias
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2018, 103 (02) : 210 - 216
[2] Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Carbamazepine Dosing
Leckband, S. G.
Kelsoe, J. R.
Dunnenberger, H. M.
George, A. L., Jr.
Tran, E.
Berger, R.
Mueller, D. J.
Whirl-Carrillo, M.
Caudle, K. E.
Pirmohamed, M.
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2013, 94 (03) : 324 - 328
[3] Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics-Guided Warfarin Dosing: 2017 Update
Johnson, J. A.
Caudle, K. E.
Gong, L.
Whirl-Carrillo, M.
Stein, C. M.
Scott, S. A.
Lee, M. T.
Gage, B. F.
Kimmel, S. E.
Perera, M. A.
Anderson, J. L.
Pirmohamed, M.
Klein, T. E.
Limdi, N. A.
Cavallari, L. H.
Wadelius, M.
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2017, 102 (03) : 397 - 404
[4] Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Abacavir Dosing: 2014 Update
Martin, M. A.
Hoffman, J. M.
Freimuth, R. R.
Klein, T. E.
Dong, B. J.
Pirmohamed, M.
Hicks, J. K.
Wilkinson, M. R.
Haas, D. W.
Kroetz, D. L.
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2014, 95 (05) : 499 - 500
[5] Clinical Pharmacogenetics Implementation Consortium Guideline for the Use of Aminoglycosides Based on MT-RNR1 Genotype
McDermott, John Henry
Wolf, Joshua
Hoshitsuki, Keito
Huddart, Rachel
Caudle, Kelly E.
Whirl-Carrillo, Michelle
Steyger, Peter S.
Smith, Richard J. H.
Cody, Neal
Rodriguez-Antona, Cristina
Klein, Teri E.
Newman, William G.
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2022, 111 (02) : 366 - 372
[6] Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2C19 Genotype and Clopidogrel Therapy: 2022 Update
Lee, Craig R.
Luzum, Jasmine A.
Sangkuhl, Katrin
Gammal, Roseann S.
Sabatine, Marc S.
Stein, Charles Michael
Kisor, David F.
Limdi, Nita A.
Lee, Yee Ming
Scott, Stuart A.
Hulot, Jean-Sebastien
Roden, Dan M.
Gaedigk, Andrea
Caudle, Kelly E.
Klein, Teri E.
Johnson, Julie A.
Shuldiner, Alan R.
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2022, 112 (05) : 959 - 967
[7] Expanded Clinical Pharmacogenetics Implementation Consortium Guideline for Medication Use in the Context of G6PD Genotype
Gammal, Roseann S.
Pirmohamed, Munir
Somogyi, Andrew A.
Morris, Sarah A.
Formea, Christine M.
Elchynski, Amanda L.
Oshikoya, Kazeem A.
McLeod, Howard L.
Haidar, Cyrine E.
Whirl-Carrillo, Michelle
Klein, Teri E.
Caudle, Kelly E.
Relling, Mary, V
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2023, 113 (05) : 973 - 985
[8] Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Abacavir Dosing
Martin, M. A.
Klein, T. E.
Dong, B. J.
Pirmohamed, M.
Haas, D. W.
Kroetz, D. L.
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2012, 91 (04) : 734 - 738
[9] Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 Genotype and Use of Ondansetron and Tropisetron
Bell, G. C.
Caudle, K. E.
Whirl-Carrillo, M.
Gordon, R. J.
Hikino, K.
Prows, C. A.
Gaedigk, A.
Agundez, J. A. G.
Sadhasivam, S.
Klein, T. E.
Schwab, M.
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2017, 102 (02) : 213 - 218
[10] Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing: 2013 Update
Relling, M. V.
Gardner, E. E.
Sandborn, W. J.
Schmiegelow, K.
Pui, C-H
Yee, S. W.
Stein, C. M.
Carrillo, M.
Evans, W. E.
Hicks, J. K.
Schwab, M.
Klein, T. E.
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2013, 93 (04) : 324 - 325

← 1 2 3 4 5 →