DNA vaccines: Successes and limitations in cancer and infectious disease

被引：33
|
作者：
Lowe, DB
Shearer, MH
Kennedy, RC
机构：
[1] Texas Tech Univ, Hlth Sci Ctr, Dept Microbiol & Immunol, Lubbock, TX 79430 USA
[2] SW Canc Treatment & Res Ctr, Lubbock, TX USA
来源：
JOURNAL OF CELLULAR BIOCHEMISTRY | 2006年 / 98卷 / 02期
关键词：
DNA vaccines; cancer; immunotherapy; infectious diseases;
D O I：
10.1002/jcb.20775
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Vaccination with plasmid DNA is an active area of investigation that is being applied to diseases including cancer and microbial pathogens associated with infectious diseases. Since its discovery, great progress has been made with the administration of DNA vaccines to initiate specific and effective immune responses against targeted illnesses. However, many obstacles still face its use in prophylactic and therapeutic vaccination scenarios. The nature of these difficulties alongside the Successes and future of plasmid DNA will be discussed.
引用
收藏
页码：235 / 242
页数：8
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