Mesoporous gadolino-aluminosilicate nanoparticles as magnetic resonance imaging contrast agents

被引：8
|
作者：
Tse, Nicholas M. K. [1 ,2 ]
Kennedy, Danielle F. [1 ]
Kirby, Nigel [3 ]
Moffat, Bradford A. [4 ]
Hinton, Tracey M. [5 ]
Muir, Benjamin W. [1 ]
Caruso, Rachel A. [1 ,2 ]
Drummond, Calum J. [1 ]
机构：
[1] CSIRO Mat Sci & Engn, Clayton, Vic 3169, Australia
[2] Univ Melbourne, Sch Chem, Melbourne, Vic 3010, Australia
[3] Australian Synchrotron, Clayton, Vic 3168, Australia
[4] Univ Melbourne, Dept Radiol, Parkville, Vic 3050, Australia
[5] CSIRO Livestock Ind, Geelong, Vic 3219, Australia
来源：
JOURNAL OF MATERIALS CHEMISTRY B | 2013年 / 1卷 / 09期
基金：
澳大利亚研究理事会;
关键词：
DRUG-DELIVERY; SILICA; RELAXATION; GLASSES;
D O I：
10.1039/c3tb00034f
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
Enhanced T-1 MRI contrast was observed in mesoporous gadolinosilicates co-doped with aluminium. The effect of gadolinium and aluminium dopant concentration was explored using a high-throughput workflow. The T-1 relaxivity increases with lower gadolinium and higher aluminium loadings.
引用
收藏
页码：1219 / 1222
页数：4
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