α-Ketoglutarate dehydrogenase complex moonlighting: ROS signalling added to the list: An Editorial highlight for "Reductions in the mitochondrial enzyme -ketoglutarate dehydrogenase complex in neurodegenerative disease - beneficial or detrimental?'

被引：7
|
作者：
Fernandez, Emilio [1 ,2 ]
Bolanos, Juan P. [1 ,2 ]
机构：
[1] Univ Salamanca, Dept Biochem & Mol Biol, Salamanca, Spain
[2] Univ Salamanca, CSIC, Inst Funct Biol & Genom IBFG, Zacarias Gonzalez 2, Salamanca 37007, Spain
来源：
JOURNAL OF NEUROCHEMISTRY | 2016年 / 139卷 / 05期
关键词：
GLYCOLYSIS; NEURONS;
D O I：
10.1111/jnc.13862
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：689 / 690
页数：2
相关论文
共 3 条
  • [1] Reductions in the mitochondrial enzyme -ketoglutarate dehydrogenase complex in neurodegenerative disease - beneficial or detrimental?
    Chen, Huanlian
    Denton, Travis T.
    Xu, Hui
    Calingasan, Noel
    Beal, M. Flint
    Gibson, Gary E.
    JOURNAL OF NEUROCHEMISTRY, 2016, 139 (05) : 823 - 838
  • [2] Oxidative metabolites of 5-S-cysteinylnorepinephrine are irreversible inhibitors of mitochondrial complex I and the α-ketoglutarate dehydrogenase and pyruvate dehydrogenase complexes:: Possible implications for neurodegenerative brain disorders
    Xin, WK
    Shen, XM
    Li, H
    Dryhurst, G
    CHEMICAL RESEARCH IN TOXICOLOGY, 2000, 13 (08) : 749 - 760
  • [3] Novel functions of the α-ketoglutarate dehydrogenase complex may mediate diverse oxidant-induced changes in mitochondrial enzymes associated with Alzheimer's disease
    Shi, Qingli
    Xu, Hui
    Kleinman, Wayne A.
    Gibson, Gary E.
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2008, 1782 (04): : 229 - 238
1