Constitutive IRAK1/4 kinase activation contributes to NF-kB activity and chemoresistance in pancreatic cancer

被引:0
|
作者
Zhang, Daoxiang
Li, Lin
Jiang, Hongmei
Yu, Jinsheng
Knolhoff, Brett
Head, Richard
Lockhart, Albert C.
DeNardo, David G.
Wang-Gillam, Andrea
Ruzinova, Marianna B.
Lim, Kian-Huat
机构
关键词
D O I
10.1158/1538-7445.AM2016-181
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
181
引用
收藏
页数:3
相关论文
共 50 条
  • [1] Constitutive IRAK4 activation contributes to NF-κB activity and chemoresistance in colorectal cancer
    Li, Qiong
    Li, Lin
    Zhang, Daoxiang
    Jiang, Hongmei
    Wang-Gillam, Andrea
    Ruzinova, Marianna B.
    Lim, Kian-Huat
    CANCER RESEARCH, 2018, 78 (13)
  • [2] NF-kB activation leads to chemoresistance in pancreatic cancersB
    K. M. Baerman
    K. Dave-Coombe
    A. Baldwin
    H. J. Kim
    Annals of Surgical Oncology, 2004, 11 : S86 - S86
  • [3] Activation of NF-KB Signaling by Inhibitor of NF-KB Kinase β Increases Aggressiveness of Ovarian Cancer
    Hernandez, Lidia
    Hsu, Sarah C.
    Davidson, Ben
    Birrer, Michael J.
    Kohn, Elise C.
    Annunziata, Christina M.
    CANCER RESEARCH, 2010, 70 (10) : 4005 - 4014
  • [4] SUMOylated CPAP contributes to NF-kB activation in cancer cells
    Yang, Shu-Ting
    Hung, Liang-Yi
    CANCER RESEARCH, 2012, 72
  • [5] Proteome analysis reveals activation of IL1/IRAK1/NF-kB axis in the healthy African American skin
    Trubetskoy, D.
    Tsoi, L. C.
    White, B. E. Perez
    Budunova, I.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2024, 144 (08) : S92 - S92
  • [6] Mitogenic and anti-apoptotic role of constitutive NF-kB/Rel activity in pancreatic cancer
    Liptay, S
    Ludwig, L
    Weber, CK
    Wagner, M
    Adler, G
    Schmid, RM
    GASTROENTEROLOGY, 2002, 122 (04) : A76 - A76
  • [7] DOES NF-KB ACTIVATION INHIBITOR, DHMEQ OVERCOME THE CHEMORESISTANCE TO CISPLATIN IN BLADDER CANCER?
    Gondo, Tatsuo
    Horiguchi, Yutaka
    Hashimoto, Takeshi
    Nakashima, Jun
    Tachibana, Masaaki
    Kikuchi, Eiji
    Oya, Mototsugu
    Suzuki, Eriko
    Umezawa, Kazuo
    JOURNAL OF UROLOGY, 2011, 185 (04): : E423 - E423
  • [8] IL1B Mediates NF-kB Activity in Pancreatic Cancer Cells
    Chandra, A.
    Nomura, A.
    McGinn, O.
    Chugh, R.
    Sangwan, V.
    Saluja, A.
    Banerjee, S.
    PANCREAS, 2013, 42 (08) : 1342 - 1342
  • [9] Constitutive IRAK4 Activation Underlies Poor Prognosis and Chemoresistance in Pancreatic Ductal Adenocarcinoma
    Zhang, Daoxiang
    Li, Lin
    Jiang, Hongmei
    Knolhoff, Brett L.
    Lockhart, Albert C.
    Wang-Gillam, Andrea
    DeNardo, David G.
    Ruzinova, Marianna B.
    Lim, Kian-Huat
    CLINICAL CANCER RESEARCH, 2017, 23 (07) : 1748 - 1759
  • [10] Inhibition of Both IRAK1 and IRAK4 Is Required for Complete Suppression of NF-Kb Signaling across Multiple Receptor-Mediated Pathways in MDS and AML
    Rosenbaum, Jan S.
    Hoyt, Scott B.
    Kolt, Amal S.
    Luedtke, Daniel A.
    Thomas, Craig J.
    Starczynowski, Daniel T.
    BLOOD, 2022, 140 : 5949 - 5950