Isolation and Characterization of Enterocin W, a Novel Two-Peptide Lantibiotic Produced by Enterococcus faecalis NKR-4-1

被引:46
|
作者
Sawa, Naruhiko [1 ]
Wilaipun, Pongtep [2 ]
Kinoshita, Seisuke [1 ]
Zendo, Takeshi [1 ]
Leelawatcharamas, Vichien [3 ]
Nakayama, Jiro [1 ]
Sonomoto, Kenji [1 ,4 ]
机构
[1] Kyushu Univ, Fac Agr, Div Appl Mol Microbiol & Biomass Chem,Grad Sch, Lab Microbial Technol,Dept Biosci & Biotechnol,Hi, Fukuoka 812, Japan
[2] Kasetsart Univ, Fac Fisheries, Dept Fishery Prod, Bangkok, Thailand
[3] Kasetsart Univ, Fac Agroind, Dept Biotechnol, Bangkok, Thailand
[4] Kyushu Univ, Bioarchitecture Ctr, Dept Funct Metab Design, Higashi Ku, Fukuoka 812, Japan
基金
日本学术振兴会;
关键词
BACTERIOCINS; CYSTINE; BONDS;
D O I
10.1128/AEM.06497-11
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Enterococcus faecalis NKR-4-1 isolated from pla-ra produces a novel two-peptide lantibiotic, termed enterocin W, comprising W alpha and W beta. The structure of enterocin W exhibited similarity with that of plantaricin W. The two peptides acted synergistically, and their order of binding to the cell membrane was important for their inhibitory activity.
引用
收藏
页码:900 / 903
页数:4
相关论文
共 24 条
  • [1] Biochemical and genetic characterization of the two-peptide bacteriocin enterocin 1071 produced by Enterococcus faecalis FAIR-E 309
    Franz, CMAP
    Grube, A
    Herrmann, A
    Abriouel, H
    Stärke, J
    Lombardi, A
    Tauscher, B
    Holzapfel, WH
    APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2002, 68 (05) : 2550 - 2554
  • [2] Purification and Characterization of Enterocin 4, a Bacteriocin Produced by Enterococcus faecalis INIA 4
    Joosten, H. M. L. J.
    NuOez, M.
    Devreese, B.
    Van Beeumen, J.
    1996, (62)
  • [3] Purification and characterization of enterocin 4, a bacteriocin produced by Enterococcus faecalis INIA 4
    Joosten, HMLJ
    Nunez, M
    Devreese, B
    VanBeeumen, J
    Marugg, JD
    APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1996, 62 (11) : 4220 - 4223
  • [4] Isolation and characterization of enterocin SE-K4 produced by thermophilic enterococci, Enterococcus faecalis K-4
    Eguchi, T
    Kaminaka, K
    Shima, J
    Kawamoto, S
    Mori, K
    Choi, SH
    Doi, K
    Ohmomo, S
    Ogata, S
    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2001, 65 (02) : 247 - 253
  • [5] Biological and molecular characterization of a two-peptide lantibiotic produced by Lactococcus lactis IFPL105
    Martínez-Cuesta, MC
    Buist, G
    Kok, J
    Hauge, HH
    Nissen-Meyer, J
    Peláez, C
    Requena, T
    JOURNAL OF APPLIED MICROBIOLOGY, 2000, 89 (02) : 249 - 260
  • [6] Isolation and characterization of enterocin EJ97, a bacteriocin produced by Enterococcus faecalis EJ97
    Gálvez, A
    Valdivia, E
    Abriouel, H
    Camafeita, E
    Mendez, E
    Martínez-Bueno, M
    Maqueda, M
    ARCHIVES OF MICROBIOLOGY, 1998, 171 (01) : 59 - 65
  • [7] Isolation and characterization of enterocin EJ97, a bacteriocin produced by Enterococcus faecalis EJ97
    A. Gálvez
    E. Valdivia
    Hikmate Abriouel
    Emilio Camafeita
    Enrique Mendez
    Manuel Martínez-Bueno
    Mercedes Maqueda
    Archives of Microbiology, 1998, 171 : 59 - 65
  • [8] Identification of a novel two-peptide lantibiotic, Haloduracin, produced by the alkaliphile Bacillus halodurans C-125
    Lawton, Elaine M.
    Cotter, Paul D.
    Hill, Colin
    Ross, R. Paul
    FEMS MICROBIOLOGY LETTERS, 2007, 267 (01) : 64 - 71
  • [9] Characterization and cloning of the genes encoding enterocin 1071A and enterocin 1071B, two antimicrobial peptides produced by Enterococcus faecalis BFE 1071
    Balla, E
    Dicks, LMT
    Du Toit, M
    van der Merwe, MJ
    Holzapfel, WH
    APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2000, 66 (04) : 1298 - 1304
  • [10] Lactococcin Q, a novel two-peptide bacteriocin produced by Lactococcus lactis QU 4
    Zendo, Takeshi
    Koga, Shoko
    Shigeri, Yasushi
    Nakayama, Jiro
    Sonomoto, Kenji
    APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2006, 72 (05) : 3383 - 3389