Metal contaminated soil from mining area caused metal accumulation and biological responses in rats

被引：0

作者：

Nakayama, Shouta M. M. ^{[1
]}

Ikenaka, Yoshinori ^{[1
]}

Muzandu, Kaampwe ^{[2
]}

Choongo, Kennedy ^{[2
]}

Yabe, John ^{[3
]}

Umemura, Takashi ^{[3
]}

Ishizuka, Mayumi ^{[1
]}

机构：

[1] Hokkaido Univ, Toxicol Lab, Grad Sch Vet Med, Kita Ku, Sapporo, Hokkaido 0600818, Japan

[2] Univ Zambia, Dept Biomed Sci, Sch Vet Med, Lusaka, Zambia

[3] Hokkaido Univ, Lab Comparat Pathol, Grad Sch Vet Med, Kita Ku, Sapporo, Hokkaido 0600818, Japan

来源：

JAPANESE JOURNAL OF VETERINARY RESEARCH | 2013年 / 61卷

基金：

日本学术振兴会;

关键词：

biological responses; metal accumulation; rat;

D O I：

暂无

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

In order to assess the effects of metal contamination on wildlife, we collected wild black rats (Rattus sp.) from mining areas (Kabwe and Chingola) and a control area (Lusaka) in Zambia and compared metal and metallothionein (MT) levels in their tissues. Furthermore, we exposed metal-contaminated soil from Kabwe to laboratory Wistar rats (Rattus norvegicus) for one year in order to determine the accumulation factors and effects of metals caused by soil exposure. Results of both the field and laboratory studies suggested that metal-contaminated soil caused accumulation and biological responses such as elevation of MT-2 mRNA expression levels in rats.

引用

页码：S79 / S81

页数：3

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