Synthesis of Polysubstituted Naphthalenes by Iron-Catalyzed [2+2+2] Annulation of Grignard Reagents with Alkynes

被引：32
|
作者：
Ilies, Laurean [1 ]
Matsumoto, Arimasa [1 ]
Kobayashi, Motoaki [1 ]
Yoshikai, Naohiko [1 ]
Nakamura, Eiichi [1 ]
机构：
[1] Univ Tokyo, Sch Sci, Dept Chem, Bunkyo Ku, Tokyo 1130033, Japan
来源：
SYNLETT | 2012年 / 16期
基金：
日本学术振兴会;
关键词：
alkynes; annulation; C-H bond activation; iron; naphthalene; SUBSTITUTED NAPHTHALENES; INTERNAL ALKYNES; ORTHO-ARYLATION; ARYL IODIDES; ARYLMAGNESIATION; ANNELATION; ACTIVATION; IMINES; ACENES; ARENE;
D O I：
10.1055/s-0032-1317077
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Iron catalyzes the oxidative [2+2+2] annulation of an arylmagnesium compound with two molecules of an internal alkyne via C-H bond activation at 0 degrees C to produce polysubstituted naphthalene.
引用
收藏
页码：2381 / 2384
页数：4
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