p53 stabilizing agent CP-31398 prevents urinary bladder tumor growth and invasion in transgenic UPII-SV40T mice

被引：0
|
作者：
Madka, Venkateshwar [1 ]
Zhang, Yuting [1 ]
Li, Qian [1 ]
Mohammed, Altaf [1 ]
Lightfoot, Stan [1 ]
Xue, Wu Re [2 ]
Kopelovich, Levy [3 ]
Rao, Chinthalapally V. [1 ]
机构：
[1] Univ Oklahoma, Hlth Sci Ctr, Oklahoma City, OK USA
[2] NYU, Med Ctr, New York, NY 10016 USA
[3] NCI, Bethesda, MD 20892 USA
来源：
CANCER RESEARCH | 2013年 / 73卷 / 08期
关键词：
D O I：
10.1158/1538-7445.AM2013-3690
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3690
引用
收藏
页数：1
相关论文
共 14 条
  • [1] p53-stabilizing Agent CP-31398 Prevents Growth and Invasion of Urothelial Cancer of the Bladder in Transgenic UPII-SV40T Mice
    Madka, Venkateshwar
    Zhang, Yuting
    Li, Qian
    Mohammed, Altaf
    Sindhwani, Puneet
    Lightfoot, Stan
    Wu, Xue-Re
    Kopelovich, Levy
    Rao, Chinthalapally V.
    NEOPLASIA, 2013, 15 (08): : 966 - +
  • [2] Licofelone, a dual COX-LOX inhibitor prevents transitional cell carcinoma of urinary bladder in UPII-SV40T transgenic mice
    Madka, Venkateshwar
    Mohammed, Altaf
    Li, Qian
    Zhang, Yuting
    Biddick, Laura
    Lightfoot, Stanley
    Wu, Xue-Re
    Kopelovich, Levy
    Steele, Vernon
    Rao, Chinthallapally V.
    CANCER RESEARCH, 2014, 74 (19)
  • [3] Pharmacokinetics and tissue and tumor exposure of CP-31398, a p53-stabilizing agent, in rats
    Kapetanovic, Izet M.
    Muzzio, Miguel
    McCormick, David L.
    Thompson, Thomas N.
    Johnson, William D.
    Horn, Thomas L.
    Mohammed, Altaf
    Rao, Chinthalapally V.
    Kopelovich, Levy
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2012, 69 (05) : 1301 - 1306
  • [4] Pharmacokinetics and tissue and tumor exposure of CP-31398, a p53-stabilizing agent, in rats
    Izet M. Kapetanovic
    Miguel Muzzio
    David L. McCormick
    Thomas N. Thompson
    William D. Johnson
    Thomas L. Horn
    Altaf Mohammed
    Chinthalapally V. Rao
    Levy Kopelovich
    Cancer Chemotherapy and Pharmacology, 2012, 69 : 1301 - 1306
  • [5] Subchronic oral toxicity and metabolite profiling of the p53 stabilizing agent, CP-31398, in rats and dogs
    Johnson, William D.
    Muzzio, Miguel
    Detrisac, Carol J.
    Kapetanovic, Izet M.
    Kopelovich, Levy
    McCormick, David L.
    TOXICOLOGY, 2011, 289 (2-3) : 141 - 150
  • [6] Chemoprevention of Urothelial Cell Carcinoma Growth and Invasion by the Dual COX-LOX Inhibitor Licofelone in UPII-SV40T Transgenic Mice
    Madka, Venkateshwar
    Mohammed, Altaf
    Li, Qian
    Zhang, Yuting
    Patlolla, Jagan M. R.
    Biddick, Laura
    Lightfoot, Stan
    Wu, Xue-Ru
    Steele, Vernon
    Kopelovich, Levy
    Rao, Chinthalapally V.
    CANCER PREVENTION RESEARCH, 2014, 7 (07) : 708 - 716
  • [7] The p53 stabilizing agent CP-31398 and multi-kinase inhibitors. Designing, synthesizing and screening of styrylquinazoline series
    Mularski, Jacek
    Malarz, Katarzyna
    Pacholczyk, Marcin
    Musiol, Robert
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 163 : 610 - 625
  • [8] CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice
    Tang, Xiuwei
    Zhu, Yucui
    Han, Lydia
    Kim, Arianna L.
    Kopelovich, Levy
    Bickers, David R.
    Athar, Mohammad
    JOURNAL OF CLINICAL INVESTIGATION, 2007, 117 (12): : 3753 - 3764
  • [9] A p53-stabilizing agent, CP-31398, induces p21 expression with increased G2/M phase through the YY1 transcription factor in esophageal carcinoma defective of the p53 pathway
    Zhong, Boya
    Shingyoji, Masato
    Hanazono, Michiko
    Thao Thi Thanh Nguyen
    Morinaga, Takao
    Tada, Yuji
    Hiroshima, Kenzo
    Shimada, Hideaki
    Tagawa, Masatoshi
    AMERICAN JOURNAL OF CANCER RESEARCH, 2019, 9 (01): : 79 - 93
  • [10] COORDINATE EXPRESSION OF THE ENDOGENOUS P53 GENE IN BETA-CELLS OF TRANSGENIC MICE EXPRESSING HYBRID INSULIN - SV40-T ANTIGEN GENES
    EFRAT, S
    BAEKKESKOV, S
    LANE, D
    HANAHAN, D
    EMBO JOURNAL, 1987, 6 (09): : 2699 - 2704
12