Melamine and Cyanuric Acid-induced Crystalluria, Uroliths, and Nephrotoxicity in Dogs and Cats

被引:36
|
作者
Osborne, Carl A. [1 ]
Lulich, Jody P. [1 ]
Ulrich, Lisa K. [1 ]
Koehler, Lori A. [1 ]
Albasan, Hasan [1 ]
Sauer, Linda [2 ]
Schubert, Gernot [3 ]
机构
[1] Univ Minnesota, Coll Vet Med, Minnesota Urolith Ctr, Dept Vet Clin Sci, St Paul, MN 55108 USA
[2] Univ Minnesota, IT Characterizat Facil, St Paul, MN 55108 USA
[3] Vivantes Klinikum Friedrichshain, Urinary Stone Lab, Berlin, Germany
基金
美国国家科学基金会;
关键词
Melamine; Cyanuric acid; Uric acid monohydrate; Nephrotoxicity; Wheat gluten; Uroliths; Crystalluria; URINARY-BLADDER; PET; CARCINOGENICITY; RECALL; RATS;
D O I
10.1016/j.cvsm.2008.09.010
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
This article discusses the 2007 recall of canned pet food because of concerns about adverse effects on kidney function of cats and dogs. The discovery of melamine and cyanuric acid in the foods is detailed. Case studies, including clinical, pathology, histology, and toxicology findings, are presented. An attempt is being made to identify the minerals in the uroliths and kidney tissues of affected animals.
引用
收藏
页码:1 / +
页数:15
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