Anticancer activity of seaweeds

被引:104
|
作者
Gutierrez-Rodriguez, Anliely G. [1 ,2 ]
Juarez-Portilla, Claudia [1 ]
Olivares-Banuelos, Tatiana [3 ]
Zepeda, Rossana C. [1 ]
机构
[1] Univ Veracruzana, Ctr Invest Biomed, Ave Dr Luis Castelazo Ayala S-N, Xalapa 91190, Veracruz, Mexico
[2] Univ Veracruzana, Programa Doctorado Ciencias Biomed, Ave Dr Luis Castelazo Ayala S-N, Xalapa 91190, Veracruz, Mexico
[3] Univ Autonoma Baja California, Inst Invest Oceanol, Km 103 Autopista Tijuana Ensenada,AP 453, Ensenada, Baja California, Mexico
关键词
IN-VITRO; ANTIPROLIFERATIVE ACTIVITY; SULFATED POLYSACCHARIDE; ANTITUMOR-ACTIVITY; BROWN SEAWEEDS; STRUCTURAL CHARACTERISTICS; CLADOSIPHON-OKAMURANUS; KAPPAPHYCUS ALVAREZII; UNDARIA-PINNATIFIDA; CHEMICAL-STRUCTURE;
D O I
10.1016/j.drudis.2017.10.019
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Cancer is a major health problem worldwide and still lacks fully effective treatments. Therefore, alternative therapies, using natural products, have been proposed. Marine algae are an important component of the marine environment, with high biodiversity, and contain a huge number of functional compounds, including terpenes, polyphenols, phlorotannins, and polysaccharides, among others. These compounds have complex structures that have shown several biological activities, including anticancer activity, using in vitro and in vivo models. Moreover, seaweed-derived compounds target important molecules that regulate cancer processes. Here, we review our current understanding of the anticancer activity of seaweeds.
引用
收藏
页码:434 / 447
页数:14
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