Embedding Sustainability into Process Development: GlaxoSmithKline's Experiences

GlaxoSmithKline (GSK) aspires to be a sustainable company and has developed a series of tools and processes to apply Green Chemistry and Engineering principles to new product development. These tools and processes are used routinely to design-out hazardous chemicals, and bring products to market more cost effectively as we believe more sustainable practices will enable GSK to produce medicines with greater efficiency in mass and energy utilization. The Eco-Design toolkit is currently composed of five modules: Green Chemistry/Technology Guide; Materials Selection Guides; FLASCTM (Fast Lifecycle Assessment for Synthetic Chemistry); Green Packaging Guide; and a Chemicals Legislation Guide. In addition, GSK has developed an EHS Milestone Aligned Process to ensure EHS and Sustainability are integrated into each phase of new product development. These tools and processes are designed to help scientists and engineers consider potential EHS and sustainability impacts from the manufacture of the raw materials through to the ultimate fate of products and wastes in the environment. In this paper, we will describe at a high-level some of these tools and processes. Examples of practical applications and some of their benefits to the company will also be covered.