Histologic and clinical significance of atypical glandular cells on pap smears

被引:19
|
作者
Daniel, A
Barreth, D
Schepansky, A
Johnson, G
Capstick, V
Faught, W
机构
[1] Univ Alberta, Royal Alexandra Hosp, Dept Obstet & Gynecol, Edmonton, AB T5H 3V9, Canada
[2] Dynacare Kasper Med Labs, Edmonton, AB, Canada
关键词
atypical glandular cells; dysplasia; cancer;
D O I
10.1016/j.ijgo.2005.08.009
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To determine the association between atypical glandular cells (AGC) on Pap smear and clinically significant histology, in a large health region. Methods: A cytologic database of over one million Pap smears was reviewed for a result of AGUS/AGC. Cytologic and histologic follow up was obtained to establish the presence of significant histology. Results: 456 patients available for follow up had AGUS/AGC cytology results (0.043% of all Pap smear. results). 197(45.2%) patients had a clinically significant diagnosis including 40 with adenocarcinoma in situ (AIS) of the cervix and 48 with endometrial cancer. Conclusion: AGC on a Pap smear is frequently associated with a clinically significant diagnosis. (c) 2005 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:238 / 242
页数:5
相关论文
共 50 条
  • [1] Histologic implications of pap smears classified as atypical glandular cells
    Haidopoulos, DA
    Stefanidis, K
    Rodolakis, A
    Pilalis, A
    Symiakaki, I
    Diakomanolis, E
    JOURNAL OF REPRODUCTIVE MEDICINE, 2005, 50 (07) : 539 - 542
  • [2] Clinicopathological significance of atypical glandular cells on cervicovaginal Pap smears
    Kim, Mi-Kyung
    Lee, Yoo Kyung
    Hong, Sung Ran
    Lim, Kyung Taek
    DIAGNOSTIC CYTOPATHOLOGY, 2017, 45 (10) : 867 - 872
  • [3] Clinical significance of a cytologic diagnosis of atypical glandular cells, favor endometrial origin, in pap smears
    Saad, RS
    Takei, H
    Liu, YLL
    Silverman, JF
    Lipscomb, JT
    Ruiz, B
    ACTA CYTOLOGICA, 2006, 50 (01) : 48 - 54
  • [4] CLINICAL SIGNIFICANCE OF ATYPICAL GLANDULAR CELLS ON PAP SMEAR
    Suh, D. S.
    Kim, K. H.
    Yoon, M. S.
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2014, 24 (09) : 592 - 592
  • [5] Clinical significance of atypical glandular cells in Pap smears: A histologic follow-up study from an older age demographic population
    Florea, A. V.
    Zhao, X.
    Bandypadhyay, S.
    Mauser, N.
    Austin, R. M.
    Dabbs, D.
    Zhao, C.
    MODERN PATHOLOGY, 2008, 21 : 73A - 73A
  • [6] Clinical significance of atypical glandular cells in Pap smears: A histologic follow-up study from an older age demographic population
    Florea, A. V.
    Zhao, X.
    Bandypadhyay, S.
    Mauser, N.
    Austin, R. M.
    Dabbs, D.
    Zhao, C.
    LABORATORY INVESTIGATION, 2008, 88 : 73A - 73A
  • [7] Atypical glandular cells of undetermined significance Pap smears: appropriate evaluation and management
    Burnett, AF
    CURRENT OPINION IN OBSTETRICS & GYNECOLOGY, 2000, 12 (01) : 33 - 37
  • [8] CLINICAL SIGNIFICANCE OF ATYPICAL GLANDULAR CELLS IN CERVICAL PAP SMEARS : AN ANALYSIS OF 329 CASES AT A SINGLE INSTITUTION
    Jang, T. K.
    Lee, S. W.
    Kim, D. Y.
    Suh, D. S.
    Kim, J. H.
    Kim, Y. M.
    Kim, Y. T.
    Nam, J. H.
    Park, J. Y.
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2017, 27 : 844 - 844
  • [9] CLINICAL SIGNIFICANCE OF ATYPICAL GLANDULAR CELLS IN CERVICAL PAP SMEARS : AN ANALYSIS OF 329 CASES AT A SINGLE INSTITUTION
    Jang, T. K.
    Lee, S. W.
    Kim, D. Y.
    Suh, D. S.
    Kim, J. H.
    Kim, Y. M.
    Kim, Y. T.
    Nam, J. H.
    Park, J. Y.
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2017, 27 : 155 - 155
  • [10] COLPOSCOPY IN PATIENTS WITH ATYPICAL GLANDULAR CELLS ON PAP SMEARS
    Gafitanu, D.
    Scripcariu, Sadiye-Ioana
    Lazar, T.
    Teleman, S.
    Grigore, Mihaela
    MEDICAL-SURGICAL JOURNAL-REVISTA MEDICO-CHIRURGICALA, 2019, 123 (02): : 282 - 287