Inhibition of FPP-synthase in osteoblasts may explain the blunting of the bone anabolic response to PTH observed after chronic exposure of rats to bisphosphonates

被引：2

作者：

Gasser, JA ^{[1
]}

Ingold, P ^{[1
]}

Rebmann, A ^{[1
]}

Susa, M ^{[1
]}

Green, JR ^{[1
]}

机构：

[1] Novartis Inst Biomed Res, CH-4002 Basel, Switzerland

来源：

BONE | 2006年 / 38卷 / 03期

关键词：

D O I：

10.1016/j.bone.2005.12.044

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：S50 / S51

页数：2

共 6 条

[1] Inhibition of FPP-synthase in osteoblasts may explain the blunting of the bone anabolic response to PTH observed after chronic exposure of rats to bisphosphonates
Gasser, J. A.
Ingold, P.
Rebmann, A.
Susa, M.
Green, J. R.
OSTEOPOROSIS INTERNATIONAL, 2006, 17 : S68 - S69
[2] Inhibition of FPP-synthase in osteoblasts may explain the blunting of the bone anabolic response to PTH observed after chronic exposure of rats to bisphosphonates
Gasser, J. A.
Ingold, P.
Rebmann, A.
Susa, M.
Green, J. R.
OSTEOPOROSIS INTERNATIONAL, 2006, 17 : S208 - S208
[3] The blunting of the bone anabolic response to PTH observed after frequently dosed bisphosphonates in rats may be explained by inhibition of farnesyl diphosphate synthase in osteoblasts.
Gasser, JA
Ingold, P
Rebmann, A
Susa, M
JOURNAL OF BONE AND MINERAL RESEARCH, 2005, 20 (09) : S78 - S79
[4] The blunting of the bone anabolic response to PTH observed after frequently dosed bisphosphonates in rats may be explained by inhibition of farnesyl diphosphate synthase in osteoblasts.
Gasser, JA
Ingold, P
Rebmann, A
Susa, M
ARTHRITIS AND RHEUMATISM, 2005, 52 (09): : S494 - S495
[5] Chronic subcutaneous, but not single intravenous dosing of rats with bisphosphonates results in reduced bone anabolic response to PTH.
Gasser, Juerg A.
Ingold, Peter
Venturiere, Andrea
Green, Jonathan R.
ARTHRITIS AND RHEUMATISM, 2006, 54 (09): : S589 - S589
[6] Chronic subcutaneous, but not single intravenous dosing of rats with bisphosphonates results in reduced bone anabolic response to PTH.
Gasser, J. A.
Ingold, P.
Venturiere, A.
Green, J. R.
JOURNAL OF BONE AND MINERAL RESEARCH, 2006, 21 : S113 - S113

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