Biomarker evaluation of a c-KIT/KDR inhibitor (OSI-930) in human, rat and non-human primate PBMCs.

被引:0
|
作者
Biesecker, G [1 ]
Li, Y [1 ]
Logan, T [1 ]
Hart, K [1 ]
Sennello, G [1 ]
Tomkinson, B [1 ]
Richardson, F [1 ]
机构
[1] OSI Pharmaceut, Boulder, CO USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:9073S / 9073S
页数:1
相关论文
共 12 条
  • [1] Inhibition of c-Kit, VEGFR-2 (KDR), and ABCG2 by analogues of OSI-930
    Patel, Jay P.
    Kuang, Ye-Hong
    Chen, Zhe-Sheng
    Korlipara, Vijaya L.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 21 (21) : 6495 - 6499
  • [2] Design, synthesis, and evaluation of OSI-930 analogs as dual c-Kit and KDR (VEGFR-2) tyrosine kinase inhibitors
    Patel, Jay
    Korlipara, Vijaya L.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238
  • [3] Systemic and pulmonary C1q as biomarker of progressive disease in experimental non-human primate tuberculosis
    Dijkman, Karin
    Lubbers, Rosalie
    Borggreven, Nicole, V
    Ottenhoff, Tom H. M.
    Joosten, Simone A.
    Trouw, Leendert A.
    Verreck, Frank A. W.
    SCIENTIFIC REPORTS, 2020, 10 (01)
  • [4] Systemic and pulmonary C1q as biomarker of progressive disease in experimental non-human primate tuberculosis
    Karin Dijkman
    Rosalie Lubbers
    Nicole V. Borggreven
    Tom H. M. Ottenhoff
    Simone A. Joosten
    Leendert A. Trouw
    Frank A. W. Verreck
    Scientific Reports, 10
  • [5] Effect of novel PKCθ selective inhibitor AS2521780 on acute rejection in rat and non-human primate models of transplantation
    Fukahori, Hidehiko
    Chida, Noboru
    Maeda, Masashi
    Tasaki, Mamoru
    Kawashima, Tomoko
    Noto, Takahisa
    Tsujimoto, Susumu
    Nakamura, Koji
    Oshima, Shinsuke
    Hirose, Jun
    Higashi, Yasuyuki
    Morokata, Tatsuaki
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2015, 27 (02) : 232 - 237
  • [6] Quinazoline derivatives as MC-I inhibitors: Evaluation of myocardial uptake using Positron Emission Tomography in rat and non-human primate
    Purohit, Ajay
    Benetti, Richard
    Hayes, Megan
    Guaraldi, Mary
    Kagan, Mikhail
    Yalamanchilli, Padmaja
    Su, Fran
    Azure, Michael
    Mistry, Mahesh
    Yu, Ming
    Robinson, Simon
    Dischino, Douglas D.
    Casebier, David
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (17) : 4882 - 4885
  • [7] Evaluation of [11C]T2310 distribution, kinetics and selectivity for phosphodiesterase-4 subtype D in non-human primate brain
    Sandiego, C. M.
    Plisson, C.
    Onega, M.
    Zasadny, K.
    Rabiner, E. A.
    Gunn, R. N.
    Nugent, R.
    Gurney, M.
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2019, 39 : 610 - 610
  • [8] The PI3Kδ selective inhibitor AS2541019 suppresses donor-specific antibody production in rat cardiac and non-human primate renal allotransplant models
    Marui, Takanori
    Fukahori, Hidehiko
    Ito, Misato
    Kaneko, Yoko
    Maeda, Masashi
    Tsujimoto, Susumu
    Morokata, Tatsuaki
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2019, 75
  • [9] Radiosynthesis and in vivo evaluation of [11C]MP-10 as a PET probe for imaging PDE10A in rodent and non-human primate brain
    Tu, Zhude
    Fan, Jinda
    Li, Shihong
    Jones, Lynne A.
    Cui, Jinquan
    Padakanti, Prashanth K.
    Xu, Jinbin
    Zeng, Dexing
    Shoghi, Kooresh I.
    Perlmutter, Joel S.
    Mach, Robert H.
    BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 19 (05) : 1666 - 1673
  • [10] 11C-fallypride:: radiosynthesis and preliminary evaluation of a novel dopamine D2/D3 receptor PET radiotracer in non-human primate brain
    Mukherjee, J
    Shi, BZ
    Christian, BT
    Chattopadhyay, S
    Narayanan, TK
    BIOORGANIC & MEDICINAL CHEMISTRY, 2004, 12 (01) : 95 - 102