A PBTK model for estragole metabolism in rat and human to improve the carcinogenic risk assessment of doses relevant to dietary human exposures

被引:0
|
作者
Punt, A
Freidig, A
Delatour, T
Scholz, G
Schilter, B
van Bladeren, PJ
Rietjens, IMCM
机构
[1] Univ Wageningen & Res Ctr, Div Toxicol, NL-6700 HB Wageningen, Netherlands
[2] TNO, Qual Life, NL-3700 AJ Zeist, Netherlands
[3] Nestle Res Ctr, CH-1000 Lausanne, Switzerland
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:172 / 172
页数:1
相关论文
共 10 条
  • [1] THE CARCINOGENIC POTENTIAL OF ETHYL CARBAMATE (URETHANE) - RISK ASSESSMENT AT HUMAN DIETARY EXPOSURE LEVELS
    SCHLATTER, J
    LUTZ, WK
    [J]. FOOD AND CHEMICAL TOXICOLOGY, 1990, 28 (03) : 205 - 211
  • [2] Quantitative microbial risk assessment model for Legionnaires' disease: Assessment of human exposures for selected spa outbreaks
    Armstrong, Thomas W.
    Haas, Charles N.
    [J]. JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE, 2007, 4 (08) : 634 - 646
  • [3] Assessment of Donor and Environmental Risk Factors in a Human Physiologically Relevant Model of Nonalcoholic Steatohepatitis (NASH)
    Feaver, Ryan E.
    Lawson, Mark
    Mackey, Aaron J.
    Manka, David
    Wamhoff, Brian R.
    Dash, Ajit
    Blackman, Brett R.
    [J]. HEPATOLOGY, 2015, 62 : 660A - 660A
  • [4] Multiple deuterated phenanthrene metabolites as probes for the metabolism of carcinogenic PAHs in humans: Phenotyping, genotyping and potential application in human health risk assessment
    Luo, Kai
    Hochalter, Jon
    Paiano, Viviana
    Wang, Jing
    Sipe, Christopher
    Carmella, Steven
    Murphy, Sharon
    Hatsukami, Dorothy
    Jensen, Joni
    Fujioka, Naomi
    Lam, Stephen
    Bergstrom, Lori
    Midthun, David
    Hecht, Stephen
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 258
  • [5] The human iPSC-cardiomyocyte arrhythmic risk (hCAR) assessment model to improve drug cardiac safety evaluation
    Guo, Liang
    Coyle, Luke
    Abrams, Rory
    Heidelberger, Cheryl
    Singer, Thomas
    Weiser, Thomas
    Chiao, Eric
    Kemper, Ray
    Kolaja, Kyle
    [J]. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2013, 68 (01) : E24 - E24
  • [6] Relative bioavailability of selenium in rice using a rat model and its application to human health risk assessment
    Qin, Yan
    Huang, Caicheng
    Huang, Guirong
    Li, Hong
    Shohag, M. J. I.
    Gu, Minghua
    Shen, Fangke
    Lu, Dan
    Zhang, Mingfu
    Wei, Yanyan
    [J]. ENVIRONMENTAL POLLUTION, 2023, 338
  • [7] Reanalysis of Trichloroethylene and Tetrachloroethylene Metabolism to Glutathione Conjugates Using Human, Rat, and Mouse Liver in Vitro Models to Improve Precision in Risk Characterization
    Valdiviezo, Alan
    Brown, Grace E.
    Michell, Ashlin R.
    Trinconi, Cristiana M.
    Bodke, Vedant V.
    Khetani, Salman R.
    Luo, Yu-Syuan
    Chiu, Weihsueh A.
    Rusyn, Ivan
    [J]. ENVIRONMENTAL HEALTH PERSPECTIVES, 2022, 130 (11)
  • [8] Bioaccessibility, dietary exposure and human risk assessment of heavy metals from market vegetables in Hong Kong revealed with an in vitro gastrointestinal model
    Hu, Junli
    Wu, Fuyong
    Wu, Shengchun
    Cao, Zhihong
    Lin, Xiangui
    Wong, Ming Hung
    [J]. CHEMOSPHERE, 2013, 91 (04) : 455 - 461
  • [9] Evaluation of the enantioselective in vitro metabolism of the chiral pesticide fipronil employing a human model: Risk assessment through in vitro-in vivo correlation and prediction of toxicokinetic parameters
    Carrao, Daniel Blascke
    dos Reis Gomes, Isabel Cristina
    Barbosa Junior, Fernando
    Moraes de Oliveira, Anderson Rodrigo
    [J]. FOOD AND CHEMICAL TOXICOLOGY, 2019, 123 : 225 - 232
  • [10] Benchmark dose risk assessment for formaldehyde using airflow modeling and a single-compartment, DNA-protein cross-link dosimetry model to estimate human equivalent doses
    Schlosser, PM
    Lilly, PD
    Conolly, RB
    Janszen, DB
    [J]. RISK ANALYSIS, 2003, 23 (03) : 473 - 487