Hsp90 chaperone machinery coexpression increases functional glucocorticoid receptor protein expression, receptor.hsp90 heterocomplex formation, and steroid binding activity

被引：0
|
作者：
Biette, Kelly M. [1 ]
Belyaev, Alexander S. [2 ]
Murphy, Patrick J. M. [1 ]
机构：
[1] Seattle Univ, Interdisciplinary Life Sci Lab, Seattle, WA 98122 USA
[2] AB Vector, San Diego, CA USA
来源：
FASEB JOURNAL | 2013年 / 27卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
784.2
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Low-level oxidative stress increases chaperone protein activity and alters steroid receptor.hsp90 heterocomplex formation
    Stone, Orrin J.
    Franklin, Hannah R.
    Murphy, Patrick J. M.
    FASEB JOURNAL, 2012, 26
  • [2] Chaperone Activity and Dimerization Properties of Hsp90α and Hsp90β in Glucocorticoid Receptor Activation by the Multiprotein Hsp90/Hsp70-Dependent Chaperone Machinery
    Morishima, Yoshihiro
    Mehta, Ranjit K.
    Yoshimura, Miyako
    Lau, Miranda
    Southworth, Daniel R.
    Lawrence, Theodore S.
    Pratt, William B.
    Nyati, Mukesh K.
    Osawa, Yoichi
    MOLECULAR PHARMACOLOGY, 2018, 94 (03) : 984 - 991
  • [3] A conserved proline in the hsp90 binding region of the glucocorticoid receptor is required for hsp90 heterocomplex stabilization and receptor signaling
    Caamaño, CA
    Morano, MI
    Dalman, FC
    Pratt, WB
    Akil, H
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (32) : 20473 - 20480
  • [4] Regulation of glucocorticoid receptor ligand-binding activity by the hsp90/hsp70-based chaperone machinery
    Kanelakis, KC
    Pratt, WB
    NUCELAR RECEPTORS, 2003, 364 : 159 - 173
  • [5] Regulation of glucocorticoid receptor steroid binding and trafficking by the hsp90/hsp70-based chaperone machinery: implications for clinical intervention
    P J M Murphy
    Leukemia, 2005, 19 : 710 - 712
  • [6] Nucleotide binding states of hsp70 and hsp90 during sequential steps in the process of glucocorticoid receptor hsp90 heterocomplex assembly
    Kanelakis, KC
    Shewach, DS
    Pratt, WB
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (37) : 33698 - 33703
  • [7] PROOF THAT HSP70 IS REQUIRED FOR ASSEMBLY OF THE GLUCOCORTICOID RECEPTOR INTO A HETEROCOMPLEX WITH HSP90
    HUTCHISON, KA
    DITTMAR, KD
    CZAR, MJ
    PRATT, WB
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1994, 269 (07) : 5043 - 5049
  • [8] Regulation of glucocorticoid receptor steroid binding and trafficking by the hsp90/hsp70-based chaperone machinery: implications for clinical intervention - Commentary
    Murphy, PJM
    LEUKEMIA, 2005, 19 (05) : 710 - 712
  • [9] Animal and plant cell lysates share a conserved chaperone system that assembles the glucocorticoid receptor into a functional heterocomplex with hsp90
    Stancato, LF
    Hutchison, KA
    Krishna, P
    Pratt, WB
    BIOCHEMISTRY, 1996, 35 (02) : 554 - 561
  • [10] Mapping the HSP90 binding region of the glucocorticoid receptor
    1600, American Society for Biochemistry and Molecular Biology Inc., Bethesda, United States (265):
12345