MULTICOMPONENT SYNTHESIS OF 1,2,3-TRIAZOL-4-YL-METHYLTHIO-3-ARYLQUINAZOLIN-4(3H)-ONE DERIVATIVES

被引：4
|
作者：
Koohshari, Majid
Dabiri, Minoo [1 ]
Salehi, Peyman [2 ]
Bahramnejad, Mahboobeh
机构：
[1] Shahid Beheshti Univ, Dept Chem, Fac Sci, GC, Tehran, Iran
[2] Shahid Beheshti Univ, Dept Phytochem, Med Plants & Drugs Res Inst, Tehran, Iran
来源：
SYNTHETIC COMMUNICATIONS | 2012年 / 42卷 / 16期
关键词：
Azide; click chemistry; propargyl bromide; quinazolinone; 1,2,3-triazole; ANTIMALARIAL ACTIVITY; SOLID-PHASE; QUINAZOLINE; 2-STYRYLQUINAZOLIN-4(3H)-ONES; CYCLOADDITION;
D O I：
10.1080/00397911.2011.558968
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel, one-pot, three-component reaction for the synthesis of novel 1,2,3-triazol-4-yl-methylthio-3-arylquinazolin-4(3H)-one derivatives using the Huisgen 1,3-dipolar cycloaddition reaction of organic azides and in situ-prepared terminal alkynes in good to excellent yields is reported.
引用
收藏
页码：2415 / 2422
页数：8
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