Silicon photonic micro-disk resonators for label-free biosensing

被引：130

作者：

Grist, Samantha M. ^{[1
]}

Schmidt, Shon A. ^{[2
]}

Flueckiger, Jonas ^{[1
]}

Donzella, Valentina ^{[1
]}

Shi, Wei ^{[1
]}

Fard, Sahba Talebi ^{[1
]}

Kirk, James T. ^{[2
]}

Ratner, Daniel M. ^{[2
]}

Cheung, Karen C. ^{[1
]}

Chrostowski, Lukas ^{[1
]}

机构：

[1] Univ British Columbia, Dept Elect & Comp Engn, 2332 Main Mall, Vancouver, BC V6T 1Z4, Canada

[2] Univ Washington, Dept Bioengn, Seattle, WA 98195 USA

来源：

OPTICS EXPRESS | 2013年 / 21卷 / 07期

基金：

美国国家科学基金会;

关键词：

REFRACTIVE-INDEX; PROTEIN-A; WAVE-GUIDE; RESONANCE SHIFTS; RING-RESONATOR; BINDING; STREPTAVIDIN; ROUGHNESS; COMPACT; ANTIGEN;

D O I：

10.1364/OE.21.007994

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Silicon photonic biosensors are highly attractive for multiplexed Lab-on-Chip systems. Here, we characterize the sensing performance of 3 mu m TE-mode and 10 mu m dual TE/TM-mode silicon photonic micro-disk resonators and demonstrate their ability to detect the specific capture of biomolecules. Our experimental results show sensitivities of 26 nm/RIU and 142 nm/RIU, and quality factors of 3.3x10(4) and 1.6x10(4) for the TE and TM modes, respectively. Additionally, we show that the large disks contain both TE and TM modes with differing sensing characteristics. Finally, by serializing multiple disks on a single waveguide bus in a CMOS compatible process, we demonstrate a biosensor capable of multiplexed interrogation of biological samples. (c) 2013 Optical Society of America

引用

页码：7994 / 8006

页数：13

共 50 条

[1] Label-free virus detection using silicon photonic microring resonators
McClellan, Melinda S.
Domier, Leslie L.
Bailey, Ryan C.
BIOSENSORS & BIOELECTRONICS, 2012, 31 (01): : 388 - 392
[2] Differential Si ring resonators for label-free biosensing
Taniguchi, Tomoya
Yokoyama, Shuhei
Amemiya, Yoshiteru
Ikeda, Takeshi
Kuroda, Akio
Yokoyama, Shin
JAPANESE JOURNAL OF APPLIED PHYSICS, 2016, 55 (04)
[3] Fiber-tip plasmonic resonators for label-free biosensing
Nyagilo, James
Chang, Shih-Hsin
Wu, Jiaqi
Hao, Yaowu
Dave, Digant P.
SENSORS AND ACTUATORS B-CHEMICAL, 2015, 212 : 225 - 228
[4] Simulation and characterization of hollow microbridge resonators for label-free biosensing
Marquez, S.
Alvarez, M.
Farina, D.
Dominguez, C.
Lechuga, L. M.
BIO-MEMS AND MEDICAL MICRODEVICES II, 2015, 9518
[5] Label-free, multiplexed biomolecular analysis using arrays of silicon photonic microring resonators
Washburn, Adam L.
Luchansky, Matthew S.
McClellan, Melinda S.
Bailey, Ryan C.
EUROSENSORS XXV, 2011, 25
[6] Label-free, multiplexed detection of bacterial tmRNA using silicon photonic microring resonators
Scheler, Ott
Kindt, Jared T.
Qavi, Abraham J.
Kaplinski, Lauris
Glynn, Barry
Barry, Thomas
Kurg, Ants
Bailey, Ryan C.
BIOSENSORS & BIOELECTRONICS, 2012, 36 (01): : 56 - 61
[7] Toward Label-Free Biosensing With Silicon Carbide: A Review
Cooper, Oren
Wang, Bei
Brown, Christopher L.
Tiralongo, Joe
Iacopi, Francesca
IEEE ACCESS, 2016, 4 : 477 - 497
[8] New ultrasensitive resonant photonic platform for label-free biosensing
Dell'Olio, Francesco
Conteduca, Donato
Ciminelli, Caterina
Armenise, Mario Nicola
OPTICS EXPRESS, 2015, 23 (22): : 28593 - 28604
[9] Design of polymer BenzoCycloButene (BCB) based silicon photonic MZI waveguide for label-free biosensing
Kumaar, S. Prasanna
Sivasubramanian, A.
OPTOELECTRONICS AND ADVANCED MATERIALS-RAPID COMMUNICATIONS, 2024, 18 (3-4): : 93 - 102
[10] Improving the performance of silicon photonic rings, disks, and Bragg gratings for use in label-free biosensing
Schmidt, Shon
Flueckiger, Jonas
Wu, WenXuan
Grist, Samantha M.
Fard, Sahba Talebi
Donzella, Valentina
Khumwan, Pakapreud
Thompson, Emily R.
Wang, Qian
Kulik, Pavel
Kirk, James
Cheung, Karen C.
Chrostowski, Lukas
Ratner, Daniel
BIOSENSING AND NANOMEDICINE VII, 2014, 9166

← 1 2 3 4 5 →