Synthesis of magnetic α-Fe2O3 and Fe3O4 hollow nanospheres for sustained release of ibuprofen

被引：23
|
作者：
Sasidharan, Manickam [1 ]
Luitel, Horn Nath [1 ]
Gunawardhana, Nanda [1 ]
Inoue, Masamichi [2 ]
Yusa, Shin-ichi [2 ]
Watari, Takanori [1 ]
Nakashima, Kenichi [1 ]
机构：
[1] Saga Univ, Fac Sci & Engn, Dept Chem, Saga 8408502, Japan
[2] Univ Hyogo, Dept Mat Sci & Chem, Himeji, Hyogo 6712280, Japan
来源：
MATERIALS LETTERS | 2012年 / 73卷
基金：
日本学术振兴会;
关键词：
alpha-Fe2O3; Fe3O4; Hollow nanospheres; Micelles; Soft-template; IRON-OXIDE NANOPARTICLES; SILICA;
D O I：
10.1016/j.matlet.2011.12.058
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
A soft template method is reported for fabrication of porous alpha-Fe2O3 and Fe3O4 hollow nanospheres of size 32 +/- 2 nm. A new triblock copolymer micelle poly(styrene-b-acrylic acid-b-ethylene oxide) with core-shell-corona architecture has been used as soft template. The hollow nanospheres were thoroughly characterized by transmission electron microscope, superconducting quantum interference device (SQUID), X-ray diffraction, nitrogen adsorption/desorption analyses, dynamic light scattering, infrared spectroscopy, and thermal analysis. The efficiency of magnetic hollow nanospheres as drug-delivery carriers was investigated using ibuprofen as a model drug. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码：4 / 7
页数：4
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