Conception and evaluation of new fluorinated COX-2 ligands to visualize and quantify neuroinflammation by PET

被引:0
|
作者
Hosselet, Christel [1 ]
Elie, Jonathan [1 ,2 ]
Toumi, Asma [1 ]
Bidault, Rudy [1 ]
Deloye, Jean-Bernard [3 ]
Routier, Sylvain [2 ]
Guilloteau, Denis [1 ,4 ]
Arlicot, Nicolas [1 ,4 ]
Buron, Frederic [2 ]
Vercouillie, Johnny [1 ,4 ]
机构
[1] CERRP, U930, Tours, France
[2] ICOA, Orleans, France
[3] Lab Cyclopharma, St Beauzire, France
[4] Tours Hosp, Tours, France
来源
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS | 2017年 / 60卷
关键词
D O I
暂无
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
P 207
引用
收藏
页码:S370 / S370
页数:1
相关论文
共 50 条
  • [1] Progress in PET Imaging of Neuroinflammation Targeting COX-2 Enzyme
    Prabhakaran, Jaya
    Molotkov, Andrei
    Mintz, Akiva
    Mann, J. John
    MOLECULES, 2021, 26 (11):
  • [2] Synthesis of PET radioligands as potential probes for imaging COX-2 in neuroinflammation
    Cortes, Michelle
    Singh, Prachi
    Morse, Cheryl
    Shrestha, Saurav
    Jenko, Kimberly
    Kowalski, Aneta
    Zoghbi, Sami
    Fujita, Masahiro
    Innis, Robert
    Pike, Victor
    JOURNAL OF NUCLEAR MEDICINE, 2015, 56 (03)
  • [3] Fluorinated COX-2 Inhibitors as Agents in PET Imaging of Inflammation and Cancer
    Uddin, Md. Jashim
    Crews, Brenda C.
    Ghebreselasie, Kebreab
    Huda, Imran
    Kingsley, Philip J.
    Ansari, Mohammad Sib
    Tantawy, Mohammed N.
    Reese, Jeffery
    Marnett, Lawrence J.
    CANCER PREVENTION RESEARCH, 2011, 4 (10) : 1536 - 1545
  • [4] Novel PET Radioligands Show That COX-2, but not COX-1, is Induced by Neuroinflammation in Rhesus Macaque
    Gallagher, Evan
    Shrestha, Stal
    Eldridge, Mark
    Cortes, Michelle
    Yu, Zu-Xi
    Lehmann, Michael
    Kim, Min-Jeong
    Singh, Prachi
    Fredericks, Megan
    Tye, George
    Saunders, Richard
    Gladding, Robert
    Liow, Jeih-San
    Fujita, Masahiro
    Zoghbi, Sami
    Pike, Victor
    Innis, Robert
    BIOLOGICAL PSYCHIATRY, 2018, 83 (09) : S160 - S160
  • [5] Neuroinflammation in Depression: PET Imaging of Translocator Protein (TSPO) and Opportunities for COX-1 And COX-2
    Innis, Robert
    Richards, Erica
    Pike, Victor
    Zarate, Carlos
    BIOLOGICAL PSYCHIATRY, 2016, 79 (09) : 2S - 3S
  • [6] Evaluation of COX-1/COX-2 selectivity and potency of a new class of COX-2 inhibitors
    Gierse, James
    Nickols, Maureen
    Leahy, Kathleen
    Warner, James
    Zhang, Yan
    Cortes-Burgos, Luz
    Carter, Jeffery
    Seibert, Karen
    Masferrer, Jaime
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2008, 588 (01) : 93 - 98
  • [7] Neuroinflammation, COX-2, and ALS - a dual role?
    Consilvio, C
    Vincent, AM
    Feldman, EL
    EXPERIMENTAL NEUROLOGY, 2004, 187 (01) : 1 - 10
  • [8] Design, synthesis and evaluation of COX-2 PET imaging probes
    Pacelli, A.
    Smith, G.
    Greenman, J.
    Cawthorne, C.
    EUROPEAN JOURNAL OF CANCER, 2014, 50 : S144 - S144
  • [9] Synthesis of a candidate brain-penetrant COX-2 PET radioligand as a potential probe for neuroinflammation
    Cortes, Michelle
    Singh, Prachi
    Morse, Cheryl
    Kowalski, Aneta
    Jenko, Kimberly
    Shrestha, Saurav
    Zoghbi, Sami
    Fujita, M.
    Innis, Robert B.
    Pike, Victor W.
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2015, 58 : S312 - S312
  • [10] Radiosynthesis and evaluation of 18F-labeled methylsulfonylpyrimidin-4-amine derivates as COX-2 PET ligands
    Kumar, Dileep
    Prabhakaran, Jaya
    Molotkov, Andrei
    Kim, Jongho
    Castrillon, John
    Doubrovin, Mikhail
    Mann, J.
    Mintz, Akiva
    JOURNAL OF NUCLEAR MEDICINE, 2020, 61