Bisphenol S exposure alters behavioral parameters in adult zebrafish and offspring

The environmental emission of bisphenol S (BPS), which is globally utilized in the manufacturing of polycarbonates, epoxy resin and thermal paper, has affected the aquatic ecosystem. Thus, effects of BPS exposure on the fitness of aquatic animals have been noted. Here, adult male and female zebrafish were used as aquatic model organisms and separately exposed to environmentally relevant doses of BPS (0, 1, 10 and 100 mu g/L) for 14 days. The results showed that BPS changed the body pigment of zebrafish and slowed the maturation of oocytes in the ovary, resulting in a significant decrease in the shoaling behavior of adult zebrafish and the attraction of BPS-treated females during the mating process. Furthermore, in the subgeneration of adult zebrafish exposed to BPS for 7 days, survival behaviors, such as locomotor, phototaxis and feeding behaviors, deviated from normal behaviors. After exposing the adult zebrafish to BPS for an additional 7 days, the above described survival behaviors and light adaptation were disrupted in offspring. Our data, based on intergenerational behavioral studies, demonstrate that BPS affects the behaviors of aquatic animals and the ability of offspring to feed and avoid predators, possibly jeopardizing the survival of aquatic animals. (C) 2020 Elsevier B.V. All rights reserved.