Pd/C-catalyzed chemoselective hydrogenation in the presence of diphenylsulfide

被引：132
|
作者：
Mori, Akinori [1 ]
Miyakawa, Yumi [1 ]
Ohashi, Eri [1 ]
Haga, Tomoko [1 ]
Maegawa, Tomohiro [1 ]
Sajiki, Hironao [1 ]
机构：
[1] Gifu Pharmaceut Univ, Med Chem Lab, Gifu 5028585, Japan
来源：
ORGANIC LETTERS | 2006年 / 8卷 / 15期
关键词：
D O I：
10.1021/ol061147j
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A Pd/C-catalyzed chemoselective hydrogenation using diphenylsulfide as a catalyst poison has been developed. This methodology selectively hydrogenates olefin and acetylene functionalities without hydrogenolysis of aromatic carbonyls and halogens, benzyl esters, and N-Cbz protective groups.
引用
收藏
页码：3279 / 3281
页数：3
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