refractory coeliac disease;
infliximab;
T lymphocytes;
D O I:
10.1097/00042737-200506000-00002
中图分类号:
R57 [消化系及腹部疾病];
学科分类号:
摘要:
Coeliac disease is generally well controlled with gluten-free diet but a small proportion of patients require corticosteroids or immunomodulatory agents. Response to anti-tumour necrosis factor (anti-TNF) agents raises interesting questions about both the pathogenesis of coeliac disease and the mechanism of action of anti-TNF agents. Refractory coeliac disease poses a therapeutic challenge to clinicians and carefully selected patients may benefit from anti-TNF therapy. (c) 2005 Lippincott Williams & Wilkins.