Environmental and Occupational Exposures in Kidney Disease

被引：28

作者：

Scammell, Madeleine K. ^{[1
]}

Sennett, Caryn M. ^{[1
]}

Petropoulos, Zoe E. ^{[1
]}

Kamal, Jeanne ^{[2
]}

Kaufman, James S. ^{[2
,3
]}

机构：

[1] Boston Univ, Sch Publ Hlth, Dept Environm Hlth, Boston, MA USA

[2] NYU, Sch Med, Div Nephrol, New York, NY USA

[3] VA New York Harbor Healthcare Syst, Div Nephrol, New York, NY 10010 USA

来源：

SEMINARS IN NEPHROLOGY | 2019年 / 39卷 / 03期

关键词：

Heavy metals; pesticides; environmental exposure; acute kidney injury; chronic kidney disease; LEPTOSPIROSIS RENAL-DISEASE; HANTAVIRUS INFECTION; DRINKING-WATER; INDUCED NEPHROTOXICITY; TUBULAR DYSFUNCTION; CADMIUM; INJURY; LEAD; GLYPHOSATE; DAMAGE;

D O I：

10.1016/j.semnephrol.2019.02.001

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

More than 8 million deaths each year are attributed to noncommunicable environmental hazards where people live, work, and play. Physical or chemical hazards may be inhaled, ingested, or absorbed through the skin, affecting all organ systems, including the kidney. Heavy metals, pesticides, and infections are some of the environmental hazards associated with kidney dysfunction and chronic kidney disease. The severity of the effects of these exposures likely is modulated by the timing and duration of exposure, genetic susceptibility, and other conditions, and may lead to the development of acute and/or chronic kidney disease. In this review, we discuss environmental exposures that are associated with kidney dysfunction in animals and human beings, with a focus on those implicated in causing chronic kidney disease. (C) 2019 Elsevier Inc. All rights reserved.

引用

页码：230 / 243

页数：14

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