Infantile spasms. Current practice and perspectives in diagnostics and therapy

被引：0
|
作者：
Lampe, C. [1 ]
von Rhein, M. [2 ,3 ]
Walther, B. [1 ]
Knuf, M. [1 ]
机构：
[1] Dr Horst Schmidt Kliniken, Klin Kinder & Jugendliche, D-65199 Wiesbaden, Germany
[2] Kantonsspital Winterthur, Dept Kinder & Jugendmed, Sozialpadiatr Zentrum, Winterthur, Switzerland
[3] Kinderspital Zurich, Abt Entwicklungspadiatrie, Zurich, Switzerland
来源：
MONATSSCHRIFT KINDERHEILKUNDE | 2015年 / 163卷 / 08期
关键词：
Infantile spasms; West syndrome; Hypsarrhythmia; Seizures; ACTH therapy; WEST-SYNDROME; OUTCOMES; CHILDREN; UPDATE; ONSET; HYPSARRHYTHMIA; CLASSIFICATION; EVOLUTION; SEIZURES; PROPOSAL;
D O I：
10.1007/s00112-015-3402-z
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Infantile spasms are an age-related epileptic encephalopathy also known as West syndrome, with a mostly unfavorable prognosis concerning development and persisting seizures. The disease is defined by seizure semiology and the typical electroencephalogram (EEG) pattern (hypsarrhythmia). Recent insights into the evolutionary process of the pathophysiology of this disease in the maturing brain possibly open up an altered approach in diagnostics and treatment. A major aim is preserving the developmental chances in children at risk. This review gives an overview on therapeutic and diagnostic guidelines and also discusses new perspectives in the comprehension of infantile epileptic encephalopathy.
引用
收藏
页码：804 / +
页数：6
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