New phenylethanoid glycosides from Veronica pectinata var. glandulosa and their free radical scavenging activities

被引：33
|
作者：
Saracoglu, I
Harput, US
Inoue, M
Ogihara, Y
机构：
[1] Nagoya City Univ, Grad Sch Pharmaceut Sci, Lab Pharmacognosy, Mizuho Ku, Nagoya, Aichi 4678603, Japan
[2] Hacettepe Univ, Fac Pharm, Dept Pharmacognosy, TR-06100 Ankara, Turkey
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 2002年 / 50卷 / 05期
关键词：
Veronica pectinata var. glandulosa; Scrophulariaceae; phenylethanoid glycoside; antioxidant; DPPH;
D O I：
10.1248/cpb.50.665
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A known phenylethanoid glycoside, ehrenoside (1), was isolated together with three new phenylethanoid glycosides, verpectoside A (2), B (3) and C (4) from the aerial parts of Veronica pectinata var. glandulosa. On the basis of spectral analysis (UV, FAB-MS, H-1-, C-13- and 2D-NMR), compounds 2-4 were determined to be 2-(3,4-dihydroxyphenyl)ethyl-O-alpha-L-arabinopyranosyl-(1 -->2)-[alpha-L-rhamnopyranosyl-(1-->3)]-(4-O-trans-feruloyl)-beta-D-glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl-O-beta-D-glucopyranosyl-(1-->2)- [alpha-L-rhamnopyranosyl-(1-->3)] (4-O-trans-caffeoyl)-beta-D-glucopyranoside and 2-(3,4-dihydroxyphenyl)ethyl-O-beta-D-glucopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1-->3)](4-O-trans-feruloyl)-beta-D-glucopyranoside, respectively. Isolated phenylethanoid glycosides exhibited potent radical scavenging activity against the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.
引用
收藏
页码：665 / 668
页数：4
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