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- [3] CPAP and Cognition in OSA (APPLES) Commentary on Kushida CA, Nichols DA, Holmes TH, et al. Effects of continuous positive airway pressure on neurocognitive function in obstructive sleep apnea patients: the Apnea Positive Pressure Long-term Efficacy Study (APPLES). SLEEP 2012; 35:1593-1602. JOURNAL OF CLINICAL SLEEP MEDICINE, 2013, 9 (05): : 516 - 517