Neuregulin-1 improved cardiac function in doxorubicin-treated mice with cardiac myocyte-specific overexpression of a dominant negative PI3K

被引:0
|
作者
Bian, Yun
Silver, Marcy
Ho, Kalon
Marchionni, Mark
Caggiano, Anthony
Kang, Peter
Morgan, James
Yan, Xinhua
机构
[1] Caritas St Elizabeths Med Ctr, Boston, MA USA
[2] Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA
[3] NRG Biotech, Arlington, MA USA
[4] Acroda Therapeut Inc, Hawthorne, NY USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
4287
引用
收藏
页数:1
相关论文
共 22 条
  • [1] Cardiomyocyte Specific Overexpression of Dominant Negative PI3K-p110α Does Not Abolish Neuregulin-1's Cardioprotective Effects in Doxorubicin-Treated Mice
    Bian, Yun
    Silver, Marcy
    Ho, Kalon K.
    Kang, Peter M.
    Morgan, James P.
    Yan, Xinhua
    CIRCULATION RESEARCH, 2009, 105 (07) : E46 - E46
  • [2] Pi3k. is a Key Modulator of Cardiac Metabolism Rewiring Occurring in Doxorubicin-Treated Mice
    Russo, Michele
    Priolo, Rebecca
    Guerra, Giulia
    Riganti, Chiara
    Hirsch, Emilio
    Ghigo, Alessandra
    CIRCULATION, 2022, 146
  • [3] Conditional Overexpression of Cardiac-Specific PI3Kα Improves Basal Myocardial Function
    Yano, Naohiro
    Zhao, Ting C.
    Tseng, Andy
    Padbury, James F.
    Tseng, Yi-Tang
    FASEB JOURNAL, 2008, 22
  • [4] Consequences of cardiac myocyte-specific ablation of KATP channels in transgenic mice expressing dominant negative Kir6 subunits
    Tong, XiaoYong
    Porter, Lisa M.
    Liu, GongXin
    Dhar-Chowdhury, Piyali
    Srivastava, Shekhar
    Pountney, David J.
    Yoshida, Hidetada
    Artman, Michael
    Fishman, Glenn I.
    Yu, Cindy
    Iyer, Ramesh
    Morley, Gregory E.
    Gutstein, David E.
    Coetzee, William A.
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2006, 291 (02): : H543 - H551
  • [5] Engineering of a transgenic mouse line with cardiac-specific conditional overexpression of PI3K
    Tseng, YT
    Yano, N
    Ianus, V
    Cathers, A
    Zhao, TC
    Padbury, JF
    FASEB JOURNAL, 2006, 20 (04): : A312 - A312
  • [6] Temporally controlled overexpression of cardiac-specific PI3Kα- a novel transgenic mouse model
    Tseng, Yi-Tang
    Yano, Naohiro
    Dahdah, John
    Cao, Tram
    Tseng, Andy
    Zhao, Ting C.
    Padbury, James F.
    FASEB JOURNAL, 2009, 23
  • [7] Gab1 Overexpression Alleviates Doxorubicin-Induced Cardiac Oxidative Stress, Inflammation, and Apoptosis Through PI3K/Akt Signaling Pathway
    Zhang, Zhaoxia
    Shen, Caijie
    Wu, Nan
    Wang, Jian
    Du, Weiping
    Chen, Xiaomin
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022, 80 (06) : 804 - 812
  • [8] Temporally controlled overexpression of cardiac-specific PI3Kα induces enhanced myocardial contractility -: a new transgenic model
    Yano, Naohiro
    Tseng, Andy
    Zhao, Ting C.
    Robbins, Jeffrey
    Padbury, James F.
    Tseng, Yi-Tang
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2008, 295 (04): : H1690 - H1694
  • [9] MiR-24-3p modulates cardiac function in doxorubicin -induced heart failure via the Sp1/PI3K signaling pathway
    Zheng, Yonghong
    Xiang, Guojian
    Zeng, Linwen
    Yang, Chao
    Ke, Jun
    Yu, Huizhen
    Zhang, Jiancheng
    CELLULAR SIGNALLING, 2024, 124
  • [10] Overexpression of coupling factor 6 attenuates exercise-induced physiological cardiac hypertrophy by inhibiting PI3K/Akt signaling in mice
    Sagara, Shigeki
    Osanai, Tomohiro
    Itoh, Taihei
    Izumiyama, Kei
    Shibutani, Shuji
    Hanada, Kenji
    Yokoyama, Hiroaki
    Yamamoto, Yuko
    Yokota, Takashi
    Tomita, Hirofumi
    Magota, Koji
    Okumura, Ken
    JOURNAL OF HYPERTENSION, 2012, 30 (04) : 778 - 786