3D printing in Ophthalmology: From medical implants to personalised medicine

被引:28
|
作者
Tan, Greymi [1 ]
Ioannou, Nicole [1 ]
Mathew, Essyrose [3 ]
Tagalakis, Aristides D. [2 ]
Lamprou, Dimitrios A. [3 ]
Yu-Wai-Man, Cynthia [1 ]
机构
[1] Kings Coll London, Fac Life Sci & Med, London SE1 7EH, England
[2] Edge Hill Univ, Dept Biol, Ormskirk L39 4QP, England
[3] Queens Univ Belfast, Sch Pharm, Belfast BT9 7BL, Antrim, North Ireland
基金
英国医学研究理事会;
关键词
3D printing; Ophthalmology; Implants; Drug delivery; Personalised medicine; DRUG-DELIVERY; GLAUCOMA;
D O I
10.1016/j.ijpharm.2022.122094
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
3D printing was invented thirty years ago. However, its application in healthcare became prominent only in recent years to provide solutions for drug delivery and clinical challenges, and is constantly evolving. This cost-efficient technique utilises biocompatible materials and is used to develop model implants to provide a greater understanding of human anatomy and diseases, and can be used for organ transplants, surgical planning and for the manufacturing of advanced drug delivery systems. In addition, 3D printed medical devices and implants can be customised for each patient to provide a more tailored treatment approach. The advantages and applications of 3D printing can be used to treat patients with different eye conditions, with advances in 3D bioprinting offering novel therapy applications in ophthalmology. The purpose of this review paper is to provide an in-depth understanding of the applications and advantages of 3D printing in treating different ocular conditions in the cornea, glaucoma, retina, lids and orbits.
引用
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页数:8
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