Primary Nasal Histiocytic Sarcoma of Macrophage-Myeloid Cell Type in a Cat

被引:11
|
作者
Wong, V. M. [1 ]
Snyman, H. N. [1 ]
Ackerley, C. [2 ]
Bienzle, D. [1 ]
机构
[1] Univ Guelph, Dept Pathobiol, Guelph, ON N1G 2W1, Canada
[2] Univ Toronto, Hosp Sick Children, Toronto, ON M5G 1X8, Canada
关键词
cat; immunohistochemistry; macrophage; round cell tumour; MALIGNANT HISTIOCYTOSIS; DISEASE;
D O I
10.1016/j.jcpa.2012.01.015
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
A 16-year-old neutered male Burmese cat was presented with a locally invasive nasal mass. The cytological and histological findings on incisional biopsy of this mass were suggestive of histiocytic sarcoma. Tumour cells expressed CD 18, major histocompatibility complex class II, lysozyme and alpha-naphthyl acetate esterase; and lacked expression of CD3, CD79a, CD1a, CD1b, calprotectin, CD11c and E-cadherin. These findings are consistent with a myeloid macrophage lineage. Metastasis to the bone marrow was present on necropsy examination. Histiocytic sarcoma should be considered in cats presented with primary round cell neoplasia of the nasal cavity. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:209 / 213
页数:5
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