Isotretinoin in the management of acne vulgaris: practical prescribing

被引：23

作者：

Fallah, Haady ^{[1
,2
]}

Rademaker, Marius ^{[3
]}

机构：

[1] Concord Repatriat Gen Hosp, Sydney, NSW, Australia

[2] Skin Hosp, Sydney, NSW, Australia

[3] Univ Auckland, Waikato Clin Campus, Hamilton, New Zealand

来源：

INTERNATIONAL JOURNAL OF DERMATOLOGY | 2021年 / 60卷 / 04期

关键词：

13-CIS RETINOIC ACID; LOW-DOSE ISOTRETINOIN; 13-CIS-RETINOIC ACID; ORAL ISOTRETINOIN; SYSTEMIC ISOTRETINOIN; PEANUT ALLERGY; TREATMENT SAFE; ALL-TRANS; EFFICACY; DERMABRASION;

D O I：

10.1111/ijd.15089

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Since it was first approved for use in 1982, isotretinoin has revolutionized the management of acne vulgaris. Despite almost four decades of widespread use, uncertainty still exists regarding the manner in which it is best prescribed. In this review, we provide an update on the pharmacokinetics, mechanism of action, contraindications, interactions, and appropriate dosing schedule of isotretinoin in the treatment of acne. We also discuss the safety of performing concurrent dermatological procedures in patients taking isotretinoin.

引用

页码：451 / 460

页数：10

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