Asplenia and functional hyposplenism in autoimmune polyglandular syndrome type 1

被引：9

作者：

Pollak, Uri ^{[1
]}

Bar-Sever, Zvi ^{[3
]}

Hoffer, Vered ^{[1
]}

Marcus, Nufar ^{[1
,2
]}

Scheuerman, Oded ^{[1
]}

Garty, Ben Zion ^{[1
,2
]}

机构：

[1] Schneider Childrens Med Ctr Israel, Dept Pediat B, IL-49202 Petah Tiqwa, Israel

[2] Schneider Childrens Med Ctr Israel Petah Tiqwa, Kipper Inst Allergy & Imunol, Tel Aviv, Israel

[3] Tel Aviv Univ, Sackler Fac Med, Div Nucl Med, IL-69978 Tel Aviv, Israel

来源：

EUROPEAN JOURNAL OF PEDIATRICS | 2009年 / 168卷 / 02期

关键词：

Asplenia; Autoimmune polyglandular syndrome; DISEASE TYPE-I; CANDIDIASIS; EXPRESSION;

D O I：

10.1007/s00431-008-0735-9

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Asplenia was diagnosed in four patients with autoimmune polyendocrine syndrome type-I (APS-I): two children, aged 2-4 years, from the same family and two adults, the father of the two children and his cousin. We have observed a worsening in splenic function in the children during a follow-up of a few years. Patients with APS-I should be evaluated for splenic function, since splenic dysfunction has important therapeutic implications, especially in children.

引用

页码：233 / 235

页数：3

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