Recent advances in the solid-phase combinatorial synthetic strategies for the quinoxaline, quinazoline and benzimidazole based privileged structures

被引：71

作者：

Kamal, A ^{[1
]}

Reddy, KL ^{[1
]}

Devaiah, V ^{[1
]}

Shankaraiah, N ^{[1
]}

Rao, MV ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2006年 / 6卷 / 01期

关键词：

D O I：

10.2174/138955706775197839

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Quinoxaline, quinazoline and benzimidazole based templates have been synthesized on solid-support employing different methodologies. This review enlightens academic and industrial examples of combinatorial synthesis for this type of, heterocycles that appeared in the literature in the last decade. Hence, some of the important synthetic strategies for the generation of quinoxaline, quinazoline and benzimidazole based privileged structures, and the important biological activities for these heterocycles have been highlighted. Further, benzothiadiazinone, thioxoquinazolinone, cinnoline and indazole are also examined in this review.

引用

页码：71 / 89

页数：19

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