Minor lupin alkaloids from the seeds of Lupinus varius and Lupinus hartwegii

A new lupin alkaloid, (-)-13 alpha-hydroxy-4-oxosparteine (1), was isolated from the chloroform fraction of an ethanol extract of the seeds of Lupinus varius together with (-)-13 alpha-hydroxysparteine. In addition, another new alkaloid, (-)-13 alpha-tigloyloxyaphylline (2), was isolated from the chloroform fraction of an ethanol extract of the seeds of Lupinus hartwegii together with (-)-17-oxosparteine, (+)-17-oxolupanine and (-)-sparteine. The structure of these alkaloids was established by spectral methods and chemical transformations.