Lower doses of self-amplifying mRNA drive superior neoantigen-specific CD8 T cell responses in cancer patients versus high doses

被引:0
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作者
Palmer, Christine D. [1 ]
Rappaport, Amy R. [2 ]
Hart, Meghan G. [1 ]
Kraemer, Lauren D. [1 ]
Kounlavouth, Sonia [1 ]
Marrali, Martina [1 ]
Jaroslaysky, Jason R. [1 ]
Nganje, Charmaine N. [1 ]
Shen, Annie [2 ]
Boucher, Gregory R. [2 ]
Kachura, Melissa A. [2 ]
Scallan, Ciaran D. [2 ]
Hong, Sue-Jean [2 ]
Gitlin, Leonid [2 ]
Spira, Alexander I. [3 ]
Kyi, Chrisann [4 ]
Catenacci, Daniel V. [5 ]
Rousseau, Raphael [2 ]
Ferguson, Andrew [1 ]
Jooss, Karin [2 ]
机构
[1] Gritstone Bio, Cambridge, MA USA
[2] Gritstone Bio, Emeryville, CA USA
[3] Virginia Canc Specialists, Fairfax, VA USA
[4] Mem Sloan Kettering Canc Ctr, New York, NY USA
[5] Univ Chicago, Chicago, IL USA
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中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
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页数:2
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