Fragment screening and structure-based drug design with G protein-coupled receptors

被引：0
|
作者：
Andrews, Steve P. [1 ]
Therapeutics, Heptares [1 ]
机构：
[1] Heptares Therapeut, Welwyn Garden City AL7 3AX, Herts, England
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2013年 / 245卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
226-MEDI
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Structure-based drug screening for G-protein-coupled receptors
    Shoichet, Brian K.
    Kobilka, Brian K.
    [J]. TRENDS IN PHARMACOLOGICAL SCIENCES, 2012, 33 (05) : 268 - 272
  • [2] Progress in Structure Based Drug Design for G Protein-Coupled Receptors
    Congreve, Miles
    Langmead, Christopher J.
    Mason, Jonathan S.
    Marshall, Fiona H.
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2011, 54 (13) : 4283 - 4311
  • [3] Importance of protein dynamics in the structure-based drug discovery of class A G protein-coupled receptors (GPCRs)
    Lee, Yoonji
    Lazim, Raudah
    Macalino, Stephani Joy Y.
    Choi, Sun
    [J]. CURRENT OPINION IN STRUCTURAL BIOLOGY, 2019, 55 : 147 - 153
  • [4] G Protein-Coupled Receptors - Targets for Fragment-based Drug Discovery
    Lawson, Alastair D. G.
    [J]. CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2015, 15 (24) : 2523 - 2527
  • [5] Stabilised G protein-coupled receptors in structure-based drug design: a case study with adenosine A2A receptor
    Andrews, Stephen P.
    Tehan, Benjamin
    [J]. MEDCHEMCOMM, 2013, 4 (01) : 52 - 67
  • [6] Heterodimerisation of G protein-coupled receptors: implications for drug design and ligand screening
    del Burgo, Laura Saenz
    Milligan, Graeme
    [J]. EXPERT OPINION ON DRUG DISCOVERY, 2010, 5 (05) : 461 - 474
  • [7] Privileged structure-based combinatorial libraries targeting G protein-coupled receptors
    Guo, T
    Hobbs, DW
    [J]. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES, 2003, 1 (04) : 579 - 592
  • [8] Engineering G Protein-Coupled Receptors for Drug Design
    Congreve, Miles
    Dore, Andrew S.
    Jazayeri, Ali
    Nonoo, Rebecca
    [J]. MULTIFACETED ROLES OF CRYSTALLOGRAPHY IN MODERN DRUG DISCOVERY, 2015, : 1 - 18
  • [9] Customizing G Protein-Coupled Receptor Models for Structure-Based Virtual Screening
    de Graaf, Chris
    Rognan, Didier
    [J]. CURRENT PHARMACEUTICAL DESIGN, 2009, 15 (35) : 4026 - 4048
  • [10] Structure-based drug discovery of G protein-coupled purine receptor ligands
    Jacobson, Kenneth
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 256
12345