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Strategies to alter the progression of Alzheimer's disease
被引:6
|作者:
Siman, R
Scott, RW
机构:
[1] Cephalon Inc., West Chester, PA 19380
关键词:
D O I:
10.1016/S0958-1669(96)80070-X
中图分类号:
Q5 [生物化学];
学科分类号:
071010 ;
081704 ;
摘要:
Recent advances in the genetics of familial Alzheimer's disease provide direction for therapeutic strategies to alter the progressive neurodegeneration. The rationale is particularly strong for targeting the deposition of amyloid into neuritic plaques, but attention has also turned to abnormalities in apoptosis and signal-transduction processes. (C) Current Biology Ltd ISSN 0958-1669..
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页码:601 / 607
页数:7
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