One-pot preparation of 4,5-disubstituted-1,2-benzoquinones

被引：0

作者：

Zhang, XC ^{[1
]}

Huang, ZS ^{[1
]}

Wei, HF ^{[1
]}

Wang, ZC ^{[1
]}

Ma, L ^{[1
]}

Gu, LQ ^{[1
]}

机构：

[1] Zhongshan Univ, Dept Chem, Canton 510275, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 1999年 / 19卷 / 02期

关键词：

oxidation; Michael addition; polyphenol oxidase; synthesis; 4,5-disubstituted-1,2-benzoquinones;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In the presence of the immobilized polyphenol oxidase, a one - pot preparation of 4,5 - disubstituted - 1,2 - benzoquinones,such as 4,5 - di - aniline - 1,2 - benzoquinone,4, 5 - di - (p - methyl aniline) - 1,2 - benzoquinone,4,5 - di - (m - chloroaniline) - 1,2 - benzoquinone and 4,5 - di - (p - bromoaniline) - 1,2 - benzoquinone,was achieved successfully by using the oxidation - Michael addition. The same results were obtained using I-2 - KI instead of the immobilized polyphenol oxidase. The proposed oxidation(Michael addition mechanism has been demonstrated by UV - Vis spectroscopy.

引用

页码：200 / 203

页数：4