MyHC and MyLC isoforms in Akhal-Teke horses of different gender and genetic background

The main purpose of this study was to investigate the relationship between MyHC and MyLC isoforms and the pedigree of the horses from different genetic background and gender. 26 Purebred Akhal-Teke horses (8 stallions and 18 mares) were used in this study, the horses belonged to 7 different sire lines and 9 different dam families. A muscle biopsy of depth 60 mm from the left gluteus medius muscle was obtained. The present study found the highest heritability for MyLC 1(fast), MYLC 2(slow) and MyHC I isoform proportions, while only the first was statistically significantly different from zero. The mares had higher proportion of MyHC IIx and MyLC 3(fast) isoforms than the stallions. No statistically significant differences were found between sire lines and dam families. However, as the heritability of MyHC and MyLC in horses is found to be of moderate value, our study does not reject the hypothesis that it could be used as additional parameter in choosing the right animals for sport and breeding. (C) 2013 Elsevier B.V. All rights reserved.