Tandem Catalysis: Synthesis of Nitrogen-Containing Heterocycles

被引:16
|
作者
Campos, Joana F. [1 ]
Berteina-Raboin, Sabine [1 ]
机构
[1] Univ Orleans, Inst Chim Organ & Analyt ICOA, Pole Chim, BP 6759,Rue Chartres, F-45067 Orleans 2, France
关键词
tandem catalysis; nitrogen heterocycles; medicinal chemistry; synthesis; ONE-POT SYNTHESIS; SUPPORTED STEREOSELECTIVE-SYNTHESIS; INTRAMOLECULAR PROTON-TRANSFER; 1,3-DIPOLAR CYCLOADDITION; EFFICIENT SYNTHESIS; CASCADE REACTION; ALKYNOIC ACIDS; EASY ACCESS; DERIVATIVES; RING;
D O I
10.3390/catal10060631
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
In this Review, we consider all the publications since the beginning of the century that describe tandem reactions resulting in the formation of five-membered aromatic nitrogen heterocycles (thiazole, imidazole, indole, tetrazole, triazole, and isoxazole). The contents of this review are organized by taxonomy and type of tandem catalysis. It covers orthogonal, auto-, and assisted tandem catalysis, providing an overview of tandem reactions applied tonitrogen heterocycles reported in the literature up to March 2020. We believe that this compilation of data will provide a necessary starting reference to developthe applications of tandem catalysis in medicinal chemistry.
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页数:53
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