Validation of Whole Blood Rapid Diagnosis Test for Hepatitis B

被引:0
|
作者
Debes, Jose D. [1 ,2 ]
van Oord, Gertine [2 ]
Boonstra, Andre [2 ]
机构
[1] Univ Minnesota, Dept Med, Box 736 UMHC, Minneapolis, MN 55455 USA
[2] Erasmus MC, Dept Gastroenterol & Hepatol, Rotterdam, Netherlands
来源
ANNALS OF GLOBAL HEALTH | 2020年 / 86卷 / 01期
关键词
D O I
10.5334/aogh.2866
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
We recently published a report validating point-of-care rapid diagnostic tests (RDT) for the diagnosis of Hepatitis B virus (HBV) infection in serum. In the current report, we validated a whole-blood RDT for HBsAg in the form of a test-strip. The test was validated in 55 HBV positive individuals across all genotypes other than F, and in 20 HBV negative individuals in the Netherlands. The RDT showed 100% sensitivity and specificity. The low cost and use in whole blood allows this RDT to be useful in resource-limited locations, further validation in such settings will be of importance.
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