Tumour necrosis factor (TNF) in psoriatic arthritis: pathophysiology and treatment with TNF inhibitors

被引：106
|
作者：
Mease, PJ [1 ]
机构：
[1] Seattle Rheumatol Associates, Seattle, WA 98104 USA
来源：
ANNALS OF THE RHEUMATIC DISEASES | 2002年 / 61卷 / 04期
关键词：
D O I：
10.1136/ard.61.4.298
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
High levels of proinflammatory cytokines, including tumour necrosis factor (TNF), have been detected in psoriatic skin lesions and joints of patients with the inflammatory disease. Early results of treatment of psoriatic arthritis and psoriasis with TNF neutralising agents are encouraging, but whether these agents will be able to improve long term outcomes, such as disability, is not yet known.
引用
收藏
页码：298 / 304
页数：7
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