A-87049, a novel potent squalene synthase inhibitor.

被引：0

作者：

Fung, AKL ^{[1
]}

Baker, WR ^{[1
]}

Fakhoury, S ^{[1
]}

Stein, HH ^{[1
]}

Cohen, J ^{[1
]}

Donner, BG ^{[1
]}

Garvey, DS ^{[1
]}

Spina, KP ^{[1
]}

Rosenberg, SH ^{[1
]}

机构：

[1] ABBOTT LABS,ABBOTT PK,IL 60064

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 1996年 / 211卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：137 / MEDI

页数：1

共 50 条

[1] Oral hypocholesterolemic activity of A-87049, a squalene synthase inhibitor in monkeys and hamsters
Lee, JY
Stein, HH
Warner, RB
Cohen, J
Devine, EM
Kovar, PJ
Hoffman, DJ
Fung, AKL
Rosenberg, SH
FASEB JOURNAL, 1996, 10 (03): : 2942 - 2942
[2] Structure activity relationship of the dicarboxylic acid portion of the squalene synthase inhibitor A-87049.
OConnor, SJ
Stein, H
Rosenberg, SH
Sullivan, GM
Fakhoury, S
Cohen, J
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1997, 214 : 220 - MEDI
[3] SYNTHESIS OF A NOVEL, POTENT INHIBITOR OF SQUALENE SYNTHASE, J-104,118
IWASAWA, Y
HAYASHI, M
SHIBATA, J
MITSUYA, M
NONOSHITA, K
HATTORI, H
ARAI, S
HIROTA, K
YONEMOTO, M
KAMEI, T
MIURA, K
NOMOTO, T
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1995, 210 : 67 - MEDI
[4] (1 alpha,2 beta,3 beta,4 alpha)-1,2-bis[[N-propyl-N-(4-phenoxybenzyl)amino]carbonyl]cyclobutane-3,4-dicarboxylic acid (A-87049): A novel potent squalene synthase inhibitor
Fung, AKL
Baker, WR
Fakhoury, S
Stein, HH
Cohen, J
Donner, BG
Garvey, DS
Spina, KP
Rosenberg, SH
JOURNAL OF MEDICINAL CHEMISTRY, 1997, 40 (14) : 2123 - 2125
[5] The synthesis of 2a-phosphohydantocidin, a potent adenylosuccinate synthase inhibitor.
Crouse, GD
Cseke, CT
Gerwick, BC
Heim, DR
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1996, 211 : 3 - AGRO
[6] Discovery of DF-461, a Potent Squalene Synthase Inhibitor
Ichikawa, Masanori
Ohtsuka, Masami
Ohki, Hitoshi
Ota, Masahiro
Haginoya, Noriyasu
Itoh, Masao
Shibata, Yoshihiro
Sugita, Kazuyuki
Ishigai, Yutaka
Terayama, Koji
Kanda, Akira
Usui, Hiroyuki
ACS MEDICINAL CHEMISTRY LETTERS, 2013, 4 (10): : 932 - 936
[7] EFFICIENT AND STEREOSELECTIVE SYNTHESIS OF J-104,118, A NOVEL, POTENT INHIBITOR OF SQUALENE SYNTHASE
IWASAWA, Y
NONOSHITA, K
TOMIMOTO, K
TETRAHEDRON LETTERS, 1995, 36 (41) : 7459 - 7462
[8] THE ISOLATION AND STRUCTURE ELUCIDATION OF ZARAGOZIC ACID-C, A NOVEL POTENT SQUALENE SYNTHASE INHIBITOR
DUFRESNE, C
WILSON, KE
ZINK, D
SMITH, J
BERGSTROM, JD
KURTZ, M
REW, D
NALLIN, M
JENKINS, R
BARTIZAL, K
TRAINOR, C
BILLS, G
MEINZ, M
HUANG, LY
ONISHI, J
MILLIGAN, J
MOJENA, M
PELAEZ, F
TETRAHEDRON, 1992, 48 (47) : 10221 - 10226
[9] Squalene synthase inhibitor
不详
DRUG DISCOVERY TODAY, 1998, 3 (03) : 142 - 142
[10] Antidiabetic properties of a new potent glycogen synthase kinase 3 inhibitor.
Luo, J
Ring, DB
Harrison, SD
Damico, C
Hensley, B
Henriksen, EJ
Wagman, AS
Ma, ST
DIABETOLOGIA, 2003, 46 : A302 - A302

← 1 2 3 4 5 →