The First Case Report of Acute Symptomatic HEV Genotype 4 Infection in an HIV-positive Patient in Japan

被引：5

作者：

Kitaura, Satoshi ^{[1
]}

Wakabayashi, Yoshitaka ^{[1
,2
]}

Okazaki, Aiko ^{[1
]}

Okada, Yuta ^{[1
]}

Okamoto, Koh ^{[1
]}

Ikeda, Mahoko ^{[3
]}

Okugawa, Shu ^{[1
]}

Moriya, Kyoji ^{[1
,3
]}

机构：

[1] Univ Tokyo Hosp, Dept Infect Dis, Tokyo, Japan

[2] Teikyo Univ, Dept Internal Med, Tokyo, Japan

[3] Univ Tokyo, Dept Infect Control & Prevent, Tokyo, Japan

来源：

INTERNAL MEDICINE | 2020年 / 59卷 / 13期

关键词：

hepatitis E; hepatitis E virus; human immunodeficiency virus; men who have sex with men; HEPATITIS-E VIRUS; AUTOCHTHONOUS INFECTIONS; NATIONWIDE SURVEY; SEROPREVALENCE; EPIDEMIOLOGY; VIROLOGY; HOKKAIDO; FEATURES;

D O I：

10.2169/internalmedicine.4505-20

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hepatitis E virus (HEV) is a common cause of acute hepatitis. Four major genotypes of HEV have been studied, with genotype 4 being the predominant genotype across Asia. We herein describe the case of a 50-year-old man with a history of human immunodeficiency virus (HIV) infection who was admitted with acute transaminitis. Serum anti-HEV-IgA and HEV-RNA were detected at the time of presentation and further testing revealed HEV genotype 4. To the best of our knowledge, this represents the first clinical case report of acute symptomatic HEV genotype 4 infection in an HIV-positive patient in Japan.

引用

页码：1655 / 1658

页数：4

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