Highly sensitive protein detection based on a novel probe with catalytic activity combined with a signal amplification strategy: assay of MDM2 for cancer staging

被引:15
|
作者
Li, Hao [1 ,2 ]
Xie, Haona [1 ,2 ]
Huang, Yue [1 ,2 ]
Bo, Bing [1 ,2 ,3 ]
Zhu, Xiaoli [4 ]
Shu, Yongqian [3 ]
Li, Genxi [1 ,2 ,4 ]
机构
[1] Nanjing Univ, Dept Biochem, Nanjing 210093, Jiangsu, Peoples R China
[2] Nanjing Univ, State Key Lab Pharmaceut Biotechnol, Nanjing 210093, Jiangsu, Peoples R China
[3] Nanjing Med Univ, Dept Oncol, Affiliated Hosp 1, Nanjing 210036, Jiangsu, Peoples R China
[4] Shanghai Univ, Sch Life Sci, Lab Biosensing Technol, Shanghai 200444, Peoples R China
基金
中国国家自然科学基金;
关键词
PEPTIDE;
D O I
10.1039/c3cc45529g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel probe with catalytic activity is used for highly sensitive MDM2 detection.
引用
收藏
页码:9848 / 9850
页数:3
相关论文
共 50 条
  • [1] A novel universal signal amplification probe-based electrochemiluminescence assay for sensitive detection of pathogenic bacteria
    Liu, Yan
    Zhu, Debin
    Cao, Yujuan
    Ma, Wenge
    Yu, Ying
    Guo, Manli
    Xing, Xiaobo
    ELECTROCHEMISTRY COMMUNICATIONS, 2017, 85 : 11 - 14
  • [2] A highly sensitive assay for matrix metalloproteinase 2 via signal amplification strategy of eATRP
    Wang, Qingyu
    Liu, Jingliang
    Yu, Shuaibing
    Sun, Haobo
    Wang, Lei
    Li, Lianzhi
    Kong, Jinming
    Zhang, Xueji
    MICROCHEMICAL JOURNAL, 2021, 164
  • [3] Highly sensitive protein detection based on aptamer probe and isothermal nicking enzyme assisted fluorescence signal amplification
    Xue, Liyun
    Zhou, Xiaoming
    Xing, Da
    CHEMICAL COMMUNICATIONS, 2010, 46 (39) : 7373 - 7375
  • [4] A highly sensitive, eco-friendly electrochemical assay for alkaline phosphatase activity based on a photoATRP signal amplification strategy
    Si, Fuchun
    Zhang, Yaping
    Lu, Jing
    Hou, Mengyuan
    Yang, Huaixia
    Liu, Yanju
    TALANTA, 2023, 252
  • [5] Highly Sensitive Colorimetric Cancer Cell Detection Based on Dual Signal Amplification
    Yu, Tao
    Dai, Pan-Pan
    Xu, Jing-Juan
    Chen, Hong-Yuan
    ACS APPLIED MATERIALS & INTERFACES, 2016, 8 (07) : 4434 - 4441
  • [6] Ultra-sensitive multiplexed detection of protein cancer biomarkers with signal amplification strategy
    Dekaliuk, M.
    FEBS OPEN BIO, 2024, 14 : 413 - 413
  • [7] Highly sensitive and selective miRNA detection based on a closed ring probe and multiple signal amplification
    Tang, Yaqin
    He, Xiao
    Zhou, Zhenxia
    Tang, Jiakun
    Guo, Rong
    Feng, Xuli
    CHEMICAL COMMUNICATIONS, 2016, 52 (96) : 13905 - 13908
  • [8] A split recognition mode combined with cascade signal amplification strategy for highly specific, sensitive detection of microRNA
    Wang, Rui
    Wang, Lei
    Zhao, Haiyan
    Jiang, Wei
    BIOSENSORS & BIOELECTRONICS, 2016, 86 : 834 - 839
  • [9] Highly sensitive electrochemiluminescence aptasensor based on dual-signal amplification strategy for kanamycin detection
    Cheng, Shuting
    Zhang, Hui
    Huang, Jingcheng
    Xu, Rui
    Sun, Xia
    Guo, Yemin
    SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 737
  • [10] A microchip electrophoresis-based fluorescence signal amplification strategy for highly sensitive detection of biomolecules
    Qin, Yingfeng
    Zhang, Liangliang
    Li, Shuting
    Zhao, Jingjin
    Huang, Yong
    Zhao, Shulin
    Liu, Yi-Ming
    CHEMICAL COMMUNICATIONS, 2017, 53 (02) : 455 - 458